Clinical Research Nurse | Guy's and St Thomas' NHS Foundation Trust

Guys and St Thomas NHS Foundation Trust; Greater London; On-site; GBP 48,000 - 57,000; Full time

Job summary

An experienced Clinical Research Nurse is sought to join the Haematology Research Team within Guy's and St Thomas' NHS Foundation Trust. You will support delivery of a growing portfolio of complex haematology trials, identify eligible patients, assist with consent, and coordinate the patient pathway from screening through to trial completion.

You must be a registered adult nurse with CPD and substantial NHS haematology research experience, with excellent communication and organisational skills,

Qualifications

• Registered adult nurse with ongoing CPD.
• Experience in clinical research, preferably haematology.
• Excellent communication and interpersonal skills.
• Ability to work independently and in MDTs.
• Strong organisational and prioritisation abilities.

Responsibilities

• Identify eligible patients from clinics and referrals.
• Assist in informed consent and entering trial data.
• Coordinate patient pathway from screening to trial completion.
• Maintain trial documentation and regulatory compliance.
• Support trial set‑up activities and trial governance.

Skills

NMC registration

Communication

Organisation

Multidisciplinary teamwork

Clinical research experience

Education

Registered adult nurse

Job description

Clinical Research Nurse | Guy's and St Thomas' NHS Foundation Trust

We are looking for an experienced, enthusiastic and motivatedResearch Nurseto join theNon- Malignant Haematology ResearchTeamwithin the Oncology and Haematology Clinical Trials service. This post will support the delivery of a high‑quality and expanding portfolio of complex Haematology research studies.

The successful candidate will work as part of the Haematology Research Team, supported by the Team Lead and senior research staff. You will be involved in identifying patients suitable for entry into clinical trials by attending clinics, screening medical notes, reviewing consultant referrals, and participating in Multidisciplinary Team (MDT) meetings. You will contribute to the informed consent process, acting as a point of support for patients and their families, and assist in coordinating the research patient pathway from screening through to trial completion, including supporting trial set‑up activities as required.

Applicants must be a registered adult nurse with evidence of continuing professional development. You should have extensive experience of clinical research in haematology within the NHS or a strong haematology clinical background with an interest in developing research skills. You will need excellent communication and interpersonal skills, the ability to organise and prioritise your workload, and the confidence to work both independently and as part of a multidisciplinary team while managing a patient caseload across several Haematology research studies

• Work autonomously to manage a caseload of complex haematology trial patients, providing duty of care and ongoing support to patients and their families throughout participation.
• Work in accordance with the Research Governance Framework, EU Clinical Trials Regulations and ICH Good Clinical Practice (GCP), ensuring protocol compliance at all times.
• Identify eligible patients by attending various Non-Malignant Haematology clinics, screening medical notes, reviewing consultant referrals, and participating in MDT meetings.
• Support the informed consent process by providing clear information and ensuring consent is obtained and documented appropriately.
• Coordinate the research patient pathway from screening through to trial closure, liaising with the trial set‑up team and using trial‑specific prompts where required.
• Maintain infection prevention and control standards, including minimising cross‑infection risk and ensuring safe disposal of body fluids and blood products.
• Administration of investigational medicinal products (IMPs) and monitor, document and report adverse events/side effects as per protocol.
• Maintain accurate, contemporaneous clinical and research records in medical/nursing notes and trial documentation.

OHCT sits within the Haematology Directorate, the team run and manage over 200 trials at any one time and cover all solid tumours and haematological malignancy and non‑malignant diseases.

We have a dedicated team running the early phase studies and part of ECMC which is based in the clinical research facility.

• Work autonomously within professional practice guidelines to manage a caseload of Non-Malignant Haematology research patients, ensuring a duty of care and providing support to patients and their families throughout trial participation.
• Work in accordance with the Research Governance Framework, EU clinical trial requirements and ICH Good Clinical Practice (GCP), ensuring trial protocols are adhered to at all times.
• Identify patients suitable for entry into Phase 1 - 3 clinical trials by attending Haematology clinics, screening medical notes, reviewing consultant referrals, and participating in Multidisciplinary Team (MDT) meetings.
• Participate in the informed consent process, acting as a resource and source of support to patients and their families, ensuring consent is appropriately obtained and documented.
• Coordinate the research patient pathway from screening through to trial closure, supporting trial set‑up activities (e.g. pathway prompts) in collaboration with the set‑up team where required.
• Maintain infection prevention and control standards, including taking adequate precautions to minimise the risk of cross‑infection and ensuring safe disposal of body fluids and blood products in line with Trust policy.
• Support delivery of trial treatments in collaboration with local nursing teams (including investigational medicinal products and advance therapy products ), and monitor, document and report adverse events/side effects in accordance with the protocol.
• Maintain accurate, contemporaneous patient records and ensure all relevant information is documented in medical and nursing notes and trial documentation.
• Complete trial documentation accurately, including Case Report Forms (CRFs), and support the collection, coordination and computerisation of data generated from clinical trials.
• Maintain clinical competence and keep up to date with current practice relevant to the role (e.g. cannulation, phlebotomy, central venous access device care, and safe handling/administration requirements for systemic anti‑cancer therapy and investigational products as required).

PORTFOLIO / STUDY DELIVERY (SUPPORTING ROLE)

• Assist with review of trial protocols and highlight practical, risk and resource implications to the Team Lead and relevant colleagues.
• Liaise with Clinical Trial Set‑Up staff to support site set‑up activities and contribute to feasibility discussions by highlighting patient pathway issues and potential mitigations to maintain patient safety.
• Support submissions and ongoing study administration as required (e.g. R&D documentation where applicable), and process amendments, ensuring information is disseminated to relevant departments.
• Work closely with the medical team and sponsor contacts to support coordination of on‑study treatment and follow‑up in line with protocol schedules.
• Contribute to accrual/activity reporting and provide information to support invoice generation where appropriate.
• Build effective working relationships across departments to support smooth trial delivery and a positive working environment.
• Provide education/updates to relevant clinical teams about the local portfolio and study requirements where appropriate.
• Participate in sharing research outputs (e.g. presentations of research activity/findings within the Trust and relevant networks) in line with service needs.
• Manage clinical incidents appropriately and promptly elevate/report incidents to the Research Team Leader in line with Trust processes.
• Maintain dialogue with the Research Team Leader regarding progress, workload and issues, attend team handover meetings, and provide cross‑cover for colleagues during annual leave, study leave and sickness as required.

PROFESSIONAL DEVELOPMENT

• Attend training and relevant education as agreed in the development plan, and attend investigator meetings and conferences when required.
• Take responsibility for maintaining professional registration and ongoing development in research practice and clinical care.
• Contribute to service development and quality improvement within the Haematology Research Team/OHCT service.
• Provide day‑to‑day support and guidance to less experienced colleagues/students as appropriate to role and competence (without formal line management responsibility).
• Participate in clinical supervision in accordance with NMC guidance and complete appraisal/performance review processes.
• Work in line with Trust policies including confidentiality/information governance, infection control, risk management and health & safety requirements.

This advert closes on Sunday 15 Nov 2026

£47,951 - £56,863 per annum inclusive of HCAS

£34,186 - £37,389 per annum inclusive of HCAs (inner) pro rata

South London and Maudsley NHS Foundation Trust