Clinical Research Fellow

London North West University Healthcare NHS Trust; Harrow; On-site; GBP 44,000 - 68,000; Full time

Job summary

A prominent NHS organization in Harrow seeks a Clinical Research Fellow to engage in both clinical and research activities focused on Ehlers-Danlos Syndromes. The role involves seeing patients under supervision, conducting genetic assessments, and participating in research on rare conditions. Suitable for registrar-level clinicians in relevant specialties, the position offers a salary ranging from £44,170 to £67,610 per annum based on experience, with a fixed-term contract for 24 months.

Qualifications

• GMC registration required.
• Eligibility to work in the United Kingdom.
• Experience managing patients with EDS or inherited connective tissue conditions.

Responsibilities

• Conduct clinical assessments and risk estimation.
• Recruit patients for the EDS study and contribute to publications.
• Attend clinical meetings and contribute to case presentations.

Skills

Clinical knowledge and skills

Experience in clinical research

Effective communication

Teaching abilities

Management and organisational skills

Education

MBBS or equivalent medical qualification

Full MRCP (UK) or full MRCP(CH)

Intercalated BSc or equivalent

Job description

Clinical Research Fellow – EDS Service

Closing Date: 17 December 2025

Overview

The successful appointee will have a combined clinical and research role within the Ehlers–Danlos Syndromes (EDS) diagnostic service. They will see patients under the supervision of EDS consultants, develop their learning in EDS and related inherited connective tissue conditions, and take part in research on rare monogenic EDS.

Main Duties

• Full‑time, fixed‑term post delivering clinics and research into rare monogenic EDS.
• Suitable for registrar‑level clinicians in Rheumatology, Clinical Genetics, Cardiology, Dermatology, Vascular Surgery or other relevant specialties.
• Base for the post is the EDS service within London North West University Healthcare NHS Trust.

Key Responsibilities

• After an observation period, prepare for weekly clinics and begin seeing patients independently with supervision.
• Conduct clinical assessments, genetic counselling, pedigree drawing and risk estimation.
• Discuss cases with genetic counsellors to improve counselling skills.
• Attend clinical meetings and multidisciplinary team (MDT) sessions and contribute to complex case presentations.
• Recruit patients to the EDS study, contribute to scientific publications, and help prepare grant applications.

Provisional Work Pattern

The job plan is negotiable and outlines the following activities:

• Monday – EDS clinical work
• Tuesday – Research work
• Wednesday – Clinical team meetings, EDS administration
• Thursday – Research and clinical administration, translational work
• Friday – EDS clinical work

About London North West University Healthcare NHS Trust

LNWH cares for the people of Brent, Ealing, Harrow and beyond. Over 8,200 clinical and support staff serve a diverse population of almost one million people. The trust includes:

• Northwick Park Hospital – One of the busiest A&E departments in the country, hosting a top‑rated hyper‑acute stroke unit.
• St Mark’s Hospital – An internationally renowned specialist centre for bowel disease.
• Ealing Hospital – A busy district general hospital with a 24/7 emergency and urgent care centre.
• Central Middlesex Hospital – Planned care site offering surgical and outpatient services.

Person Specification – Registration

• GMC registration.

Qualifications

• MBBS or equivalent medical qualification.
• Eligibility to work in the United Kingdom.
• Full MRCP (UK) or full MRCP(CH) at the time of application.
• Intercalated BSc or equivalent.

Knowledge and Expertise

• Up-to-date clinical knowledge and fit to practise safely.
• Evidence of experience in adult or paediatric medicine.
• Proven experience in clinical research.
• Experience of managing patients with EDS and/or inherited connective tissue conditions.

Teaching

• Experience teaching undergraduates, postgraduates and junior medical staff.
• Evidence of ongoing interest and achievement in research.

Management and Audit

• Understanding of clinical governance principles.
• Ability to organise and prioritise workload effectively.
• Experience of research governance procedures.
• Strategic planning and sound judgement in conflicting pressures.
• IT skills and computer literacy.
• Understanding and experience of audit.
• Current study or qualification towards a management qualification.
• Evidence of service audit, design or change management.

Research/Publication

• Knowledge of research methodology.
• Training in research methodology.
• Publications in peer‑review journals.
• Presentations to learned societies.

Language

• Proficiency in speaking and writing English at the appropriate standard for the role.

Personal Skills

• Energy, enthusiasm, and the ability to work under pressure.
• Commitment to delivering a high‑quality service with patient welfare at the forefront.
• Caring attitude towards patients.
• Effective communication with colleagues, patients, relatives, GPs, nurses and other agencies.
• Initiative and ability to work independently and in a team.
• Accuracy and ability to work under pressure.
• Positive, flexible approach in a small team of experts.
• Commitment to Continuing Medical Education and Professional Development.

Disclosure and Barring Service Check

This post requires a Disclosure and Barring Service check under the Rehabilitation of Offenders Act (Exemptions Order) 1975.

Salary

£44,170 – £67,610 per annum (depending on experience).

Contract

Fixed‑term (24 months).

Working Pattern

Full‑time.

Reference Number

337-MS-1885-SM.

Job Location

Ehlers‑Danlos Diagnostic Service, St Mark’s & Northwick Park Hospitals, Level 8.