Clinical Research Fellow

University College London Hospitals NHS Foundation Trust; Greater London; On-site; GBP 53,000; Full time

Job summary

A leading NHS trust is seeking a Clinical Research Fellow to join their neurology department. The role involves participating in clinical drug trials, conducting neurological research, and contributing to a multi-disciplinary team. Applicants must have a medical degree and GMC registration, alongside experience in neurology. The position offers a competitive annual salary of £52,656 along with various employee benefits. This is a full-time, fixed-term role for 12 months, based at the National Hospital for Neurology & Neurosurgery in London.

Benefits

Interest-free season ticket loan

Subsidised social club

Gym access

Free independent and confidential support

Qualifications

• Eligible for full registration with the GMC and hold a current licence to practise.
• Experience in pediatrics, neurology, or clinical genetics.
• Proven knowledge of GPC guidelines.

Responsibilities

• Provide clinical and research input into the Centre's research programme.
• Act as sub-investigator in clinical drug trials.
• Participate in basic research and observational studies.

Skills

Clinical research experience

Communication skills

Ability to work autonomously

Teaching experience

Interpersonal skills

Education

Medical Degree

GMC registration

Job description

Go back University College London Hospitals NHS Foundation Trust

Clinical Research Fellow

The closing date is 04 January 2026

Clinical Research Fellow- UCL/UCLH Institute of Neurology, Ataxia CentreApplications are invited for a Clinical Research Fellow in the Ataxia Centre, UCL/UCLH Department of Neuroscience and Neurogenetics, UCL Institute of Neurology, under the supervision of Prof Paola Giunti. The post offers an exciting opportunity to gain experience of translational research as part of an internationally recognised multi‑disciplinary team. The postholder will be an essential member of the research team at the Ataxia Centre, providing clinical and research input into the Centre's research programme into Ataxia and will work closely with the Principal Investigators (PIs), Clinical Research Fellows and Clinical Trials nurses. Their primary role will be as sub‑investigator in clinical drug trial: A phase 1/2a, open‑label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of intrathecally administered VO659 in participants with spinocerebellar ataxia types 1, 3, assessing the safety of this novel Antisense oligonucleotide (ASO) treatment in patients with these rare diseases. He/she will also have the opportunity to participate in current basic and observational research including longitudinal studies of dominant and recessive ataxias and at‑risk groups and healthy volunteers to identify reliable biomarkers of disease and develop new therapeutic targets.

Main duties of the job

Applicants should have a medical degree and full GMC Registration, and have previous experience in neurology, or general medicine and excellent skill in performing lumbar puncture. The successful candidate will have good inter‑personal skills, the ability to work co‑operatively in a multidisciplinary setting and the ability to demonstrate a record of academic clinical excellence. We offer our permanent staff an interest‑free season ticket loan for travel, a subsidised social club including gym, a library for staff to use, free independent and confidential support for all staff, large retail discounts, car leasing scheme and on‑site accommodation to name a few.

Please note that if you have not heard from us within 3 weeks of the closing date of the advert, you should assume that you have not been shortlisted on this occasion.

About us

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top‑quality patient care, excellent education, and world‑class research.

We provide first‑class acute and specialist services across eight sites:

• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre
• The Hospital for Tropical Diseases
• University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

Job responsibilities

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

Please note, due to anticipated high volumes of applications, this vacancy may close earlier than the listed closing date. You are advised not to delay submitting your completed application.

Come and be a part of the best NHS trust in England to work for, according to our staff*

* UCLH top trust to work at in England – In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England for the third year in a row.

UCLH recognises the benefits of flexible working for staff. To find out more, visit: Flexible working.

To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

Person Specification

Knowledge and Qualifications

• Educated to degree level (Medical Degree)
• Eligible for full registration with the GMC, eligible to apply for GMC Specialist Register, at time of appointment and hold a current licence to practise.
• Experience in paediatrics, neurology, or clinical genetics
• MCRP or equivalent
• Proven Knowledge of GPC guidelines
• Completed/working towards degree in the speciality or related field

Experience

• Clinical research experience/understanding of research methodology
• Experience of pediatrics, neurology and/or clinical genetics
• Experience in delivering evidence-based practice
• Experience of explaining complex concepts to patients in a clear and simplified manner with a very high level of consideration & care for patients, their careers and families
• Experience of formal/informal teaching of patients and staff
• Experience of acting as a patient advocate
• Experience of working with patients (children /adults) with neurodegenerative disorders
• Experience of working in the NHS

Skills and Abilities

• Previous experience in audit and evaluation
• Ability to work under own initiative
• Able to work autonomously with supervision
• Able to work across organisational and professional boundaries
• Experience of formal/informal teaching of patients and staff
• Experience of acting as a patient advocate

Communication

• Proven ability to communicate effectively in writing
• Proven ability to communicate verbally
• Good inter‑personal skills with an ability to work co‑operatively in a multidisciplinary setting.
• Medical and scientific writing skills

Personal and People Development

• Takes responsibility for own personal development plan

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

University College London Hospitals NHS Foundation Trust

Address

National Hospital for Neurology & Neurosurgery, UCLH

£52,656 a year Per annum + London Weighting

Contract

Fixed term

Duration

12 months

Working pattern

Full-time

Reference number

309-UCLH-6730-A

Job locations

National Hospital for Neurology & Neurosurgery, UCLH