Clinical Operations Manager

Hlx Life Sciences; England; Hybrid; GBP 70,000 - 90,000; Full time

Job summary

A growing biotech company in the United Kingdom is seeking a Clinical Operations Manager/Lead to oversee oncology clinical trials. The role involves managing CROs and vendors, developing clinical operations strategies, and ensuring quality delivery of clinical programmes. Ideal candidates will have a degree in Life Sciences, an extensive background in clinical operations with at least 3 years in a leadership role, and specific expertise in oncology. This position offers competitive benefits and the chance to shape operations in a fast-paced environment.

Benefits

Competitive compensation package

Company benefits

Hybrid working flexibility

Qualifications

• Minimum of 3 years of experience in a leadership role in clinical operations.
• Strong background in oncology and/or cell therapy.
• Expertise in study start-up and clinical trial execution.

Responsibilities

• Lead planning, start-up, execution, and delivery of oncology clinical trials.
• Manage CROs, vendors, and clinical sites.
• Develop and implement clinical operations strategies and budgets.

Skills

Clinical operations management

Project planning

Vendor management

Cross-functional collaboration

Communication skills

Organisational skills

Education

Degree in Life Sciences or related field

Job description

About the Company

An emerging biotech developing first-in-class T cell therapies designed to drive solid tumours into complete remission. Backed by leading life science investors and founded by experts in immunotherapy, the company is translating breakthrough science into transformative cancer treatments.

The Role

The Clinical Operations Manager / Lead will oversee and deliver clinical programmes across early and late-stage oncology studies. This role offers a unique opportunity to join a fast-growing, mission-driven biotech at a formative stage, shaping the clinical operations strategy and execution framework.

Key Responsibilities

• Lead the planning, start-up, execution, and delivery of oncology clinical trials.
• Manage CROs, vendors, and clinical sites, ensuring quality and on‑time delivery.
• Drive all aspects of study start‑up, including site feasibility, selection, activation, and essential documentation.
• Develop and implement clinical operations strategies, budgets, and SOPs.
• Collaborate cross‑functionally with translational science, regulatory, and programme teams to align operational goals.
• Build scalable systems and processes for efficient trial management and oversight.

Ideal Candidate

• Degree in Life Sciences or related field.
• Proven experience in clinical operations within biotech or pharma, including 3+ years in a leadership role.
• Strong background in oncology and/or cell therapy is necessary.
• Demonstrated expertise in study start‑up and clinical trial execution.
• Skilled in vendor management, project planning, and cross‑functional collaboration.
• Hands‑on, proactive leader with exceptional communication and organisational skills.

What’s on Offer

• Opportunity to establish and shape the clinical operations function in a high‑growth environment where you can have real impact.
• Collaborative, science‑driven culture focused on improving patient outcomes.
• Competitive compensation package, company benefits and hybrid working flexibility.