Chief Medical Officer

Barrington James Limited; Greater London; On-site; GBP 200,000 +; Full time

Job summary

A biotech company in the UK is seeking an experienced clinical leader to advance their immunology pipeline in preparation for their first-in-human clinical study. The ideal candidate will have an MD, board certification in immunology strongly preferred, and significant experience in clinical development, especially in early-phase trials. This is a unique opportunity to shape the clinical and scientific strategy at a pivotal stage.

Qualifications

• Board certification in immunology preferred.
• Proven track record in early-phase and FIH clinical trials.
• Scientific expertise in immunology and immune-mediated diseases.
• Senior clinical leadership experience in biotech or pharma.

Responsibilities

• Provide leadership as the company progresses to first-in-human studies.
• Oversee design and execution of clinical trials.
• Lead interactions with regulatory authorities.
• Build and guide a high-performing clinical function.
• Collaborate with executives and investors on development strategy.

Skills

Strategic clinical leadership

Experience in early-phase clinical trials

Regulatory interaction

Clinical and medical affairs function building

Entrepreneurial mindset

Education

MD (board-certified in immunology)

Job description

I’m currently partnering with an innovative biotech company advancing a novel immunology pipeline and preparing for their first-in-human clinical study. This is a unique opportunity to join at a pivotal stage and shape the clinical and scientific strategy from the ground up.

Key Responsibilities:

• Provide strategic clinical leadership as the company progresses from preclinical into FIH studies.
• Oversee the design, execution, and medical oversight of early-phase clinical trials.
• Lead interactions with global regulatory authorities to support IND and trial initiation.
• Build and guide a high-performing clinical and medical affairs function.
• Partner with executive leadership, board members, and investors to drive long-term development strategy.

Ideal Profile:

• MD (board-certified in immunology is strongly preferred).
• Significant clinical development experience, with a proven track record in early-phase and FIH trials.
• Deep scientific expertise in immunology and immune-mediated diseases.
• Entrepreneurial mindset with the ability to thrive in a lean, fast-paced biotech environment.
• Previous CMO or senior clinical leadership experience in biotech or pharma.