Biostatistics Lead — Senior Principal Statistician

Jazz Pharmaceuticals; Greater London; On-site; GBP 90,000 - 130,000; Full time

Job summary

Jazz Pharmaceuticals is seeking a Senior Principal Statistician, Biostatistics, to lead statistical design and analysis across Phase I–IV studies and regulatory filings. You will develop statistical strategies, oversee analyses, and collaborate with clinical and regulatory teams to ensure robust, timely deliverables.

The role requires advanced expertise in SAS/R, CDISC standards, and strong communication for cross-functional collaboration.

Qualifications

• Experience in statistical design and analysis of Phase I–IV trials.
• Proficiency with SAS and R; familiarity with CDISC standards.
• Knowledge of regulatory guidelines (ICH/CDISC) and submissions.

Responsibilities

• Lead statistical aspects of studies and integrated summaries.
• Design, analyze, validate, and document clinical trials.
• Collaborate with cross-functional teams and CROs.
• Provide statistical input for regulatory submissions.

Skills

Statistical design and analysis

SAS

R programming

Regulatory knowledge

CDISC standards

Communication skills

Team leadership

Clinical trial methodology

Project management

Data management

Education

MS/MPH in statistics or related

PhD in statistics or related (optional)

Tools

SAS

R

CDISC tools

Job description

Jazz Pharmaceuticals is seeking a Senior Principal Statistician, Biostatistics, to lead statistical design and analysis across Phase I–IV studies and regulatory filings. You will develop statistical strategies, oversee analyses, and collaborate with clinical and regulatory teams to ensure robust, timely deliverables.

The role requires advanced expertise in SAS/R, CDISC standards, and strong communication for cross-functional collaboration.