Biocatalysis Researcher

Johnson Matthey; Wendy; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leader in sustainable technology is seeking a Biocatalysis Researcher in the United Kingdom. You will conduct research applying bio-catalysis to synthesize APIs, discover novel enzymes, and support various R&D projects while working onsite. Ideal candidates hold a BSc in relevant fields and possess strong skills in protein expression and assay development. Competitive perks are offered, including retirement savings and medical plans.

Benefits

Retirement savings

Share plans

Saving accounts

Life assurance and income protection

Medical plans / health assessments

Fitness discounts

Qualifications

• BSc in Biochemistry, Molecular Biology or equivalent experience.
• Experience in cloning and protein expression.
• Desirable to have assay method development experience.

Responsibilities

• Conduct research on bio-catalysis in synthesis of APIs.
• Discover and evaluate novel enzymes for organic synthesis.
• Support R&D biocatalytic projects and customers.

Skills

Protein expression in E.coli or yeast

Cloning and protein expression

Assay method development using chromatographic equipment

Aseptic culture technique

Excellent communication skills

Problem-solving skills

Education

BSc in Biochemistry, Molecular Biology or equivalent

Tools

HPLC

UPLC

GC

UV/Vis spectrophotometer

Job description

World-changing careers, enabled by Johnson Matthey. With more than 200 years history, join us and help to accelerate the transition to net-zero! As the Biocatalysis Researcher, you'll contribute to JM's mission as a world leader in sustainable technology, transforming energy and reducing carbon emissions for a cleaner, brighter future.

We are seeking someone to conduct research on the application of bio-catalysis, aiming at implementing them in the synthesis of APIs and other fine chemicals.

You will provide support to research projects that generate new products, processes and understanding of commercial value to JM whilst building fundamental understanding of the science involved.

You will work with guidance to a generally defined project plan; evidence of working independently within area of expertise typically with a daily/weekly focus.

As the Biocatalysis Researcher, you will help drive our goals by:

• Discover, characterise and evaluate novel enzymes for organic synthesis
• Clone and express recombinant DNA using advanced molecular biology techniques
• Utilise various expression systems (e.g. E.coli, yeast) to achieve high titers of functional proteins
• Characterise enzymes using standard biochemical assays (e.g., activity assays, protein quantification)
• Provide support to projects for customers, internal R&D biocatalytic projects and bio-catalysis development
• Conduct work requiring independent judgement in the evaluation, selection, adaptation and modification of standard techniques, processes and criteria relating to the development and application of biocatalysis

Key skills that will help you succeed in this role

• BSc in Biochemistry, Molecular Biology or equivalent experience
• Perform routine protein expression in E.coli or yeast cells for use in biocatalytic applications
• Experience in cloning, expression of protein
• Desirable assay method development and validation using chromatographic equipment such as HPLC/UPLC/GC and UV/Vis spectrophotometer
• Good aseptic culture technique
• Excellent communication skills with the ability to communicate with varied audiences effectively
• Be self-motivated with strong problem-solving skills and excellent attention

Graduates considered with relevant under grad experience

Lab based role 5 days a week onsite

Even if you only match some of the skills, we'd love to hear from you to discuss further!

What we offer:

• Retirement savings
• Share plans
• Saving accounts
• Life assurance and income protection
• Medical plans / health assessments
• Fitness discounts

At JM, inclusivity is central to our values. We create an environment where everyone can thrive, embracing diverse perspectives to tackle challenges and ensure all colleagues feel valued and connected.