Postdoctoral position in cancer metabolism

Inserm; France; Sur place; EUR 30 000 - 45 000; Plein temps

Résumé du poste

A leading research institute in France is seeking a Postdoc to explore metabolic reprogramming in cancer through the p53 suppression pathway. The role involves phenotypic characterization of genetically engineered mouse models and liver cells. Candidates should have a PhD and proficiency in RNA modification analysis, mass spectrometry, and proteomics. The position is funded temporarily and starts on 1 Jan 2026.

Responsabilités

• Characterize metabolic functions of the p53 pathway in liver metabolism.
• Conduct phenotypic characterization of genetically engineered mouse models and primary liver cells.

Connaissances

Analyses of RNA modifications

Translation

Metabolism

Mass spectrometry

Proteomics

Formation

PhD or equivalent

Description du poste

IRCM - Cancer Research Institute of Montpellier

Organisation/Company Inserm Department IRCM - Cancer Research Institute of Montpellier Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Country France Application Deadline 21 Dec 2025 - 17:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Metabolic reprogramming is a hallmark of cancer cells. Understanding the downstream molecular consequences of these metabolic changes offers potential new therapeutic opportunities.

Our lab has identified previously unknown links between several key components of the p53 tumor suppressor pathway and metabolism. Our objective is to further characterize these metabolic functions of the p53 pathway in liver metabolism using a unique collection of genetically engineered mouse models in which we inactivated one, two or three components of this molecular cascade.

The post‑doc will be in charge of the phenotypic characterization of these animal models and primary liver cells (cholangiocytes, hepatocytes) derived from these animals.

Where to apply

E‑mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

• Analyses of RNA modifications
• Translation
• Metabolism
• Mass spectrometry
• Proteomics