Postdoc in Cancer Biology and Microenvironment

Institut Pasteur; France; Sur place; EUR 40 000 - 50 000; Plein temps

Résumé du poste

A leading research institute in France is seeking a Postdoctoral Fellow in Cancer Biology. Qualified candidates should have a recent PhD and experience with in vivo cancer models. The role involves investigating cancer mechanisms and requires expertise in flow cytometry. This position offers comprehensive healthcare coverage and 6 weeks paid annual leave, available immediately in a collaborative research environment in Paris.

Prestations

Comprehensive healthcare coverage

6 weeks paid annual leave

Qualifications

• At least one accepted publication and lab experience in breast cancer, lung cancer, antitumor immunity, vascular biology, stromal/mesenchymal cells.
• Excellent level of English.

Responsabilités

• Study mechanisms of tumor initiation and resistance.
• Identify novel mechanisms regulating the tumor microenvironment and antitumor immunity.
• Perform experiments using flow cytometry and other advanced methods.

Connaissances

Solid experience with in vivo cancer murine models

Flow cytometry

Transcriptomic analysis

Scripting languages (R)

Experience in epigenetic analysis

Formation

Recent PhD degree in tumor biology, vascular biology, immunology or related biomedical field

Description du poste

Organisation/Company Institut Pasteur Department Immunology Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Country France Application Deadline 31 Dec 2025 - 12:00 (Europe/Paris) Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Our laboratory has one position available for postdoctoral fellow in the area of Cancer Biology and Microenvironment . We are interested in mechanisms oftumor initiation and resistance , with an emphasis on tissue long lived cells such as stromal cells, and their crosstalk with tumor cells, immune cellsand the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics , spatial transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using these approaches, we previously identified an essential role for specific subsets of stromal cells in tissue repairand antitumor immunity (Dulauroy et al., Nature Medicine 2012; Stzepourginski et al., PNAS 2017; Jacob et al., Cell Stem Cell 2022; Di Carlo et al., Nature Immunology 2023). Building on these findings, we aim at identifying novel mechanisms regulating the tumor microenvironment and antitumor immunity , with a focus on solid tumors such asbreast cancer and lung cancer.

For more information and to apply, send a motivation letter, CV and contact information for 2 references to Lucie Peduto ( [e-mail] ).

The position is available starting immediately. Benefits include comprehensive healthcare coverage and 6 weeks paid annual leave. Research will be conducted at Institut Pasteur in the center of Paris, which contains state of-the-art facilities and a highly collaborative research environment with 13 Departments across Biology/Physics/Biomedical fields.

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

Required qualifications : Recent PhD degree (including in late 2025) in tumor biology, vascular biology , immunology or related biomedical field, with at least one accepted publication and lab experience in one or more areas that include: breast cancer, lung cancer, antitumor immunity, vascular biology, stromal/mesenchymal cells. Highly motivated candidates with interestin areas of research at theintersection of tumor biology, the stromal microenvironment and immunology are strongly encouraged to apply.

Specific Requirements

• Required: Solid experience with in vivo cancer murine models (breast cancer and/or lung cancer) and flow cytometry
• Desirable: Previous experience in transcriptomic analysis (scRNAseq) , scripting languages (R) and Seurat.
• Would be a plus: Previous experience in epigenetic analysis

Languages ENGLISH Level Excellent

Research Field Biological sciences » Biology Years of Research Experience None

Additional Information

The position is available starting immediately. Benefits include comprehensive healthcare coverage and 6 weeks paid annual leave. Research will be conducted at Institut Pasteur in the center of Paris, which contains state of-the-art facilities and a highly collaborative research environment with 13 Departments across Biology/Physics/Biomedical fields

Eligibility criteria

Candidates with a PhD defense in late 2025 are particularly encouraged to apply