Post-doctoral Research Associate

INSERM; France; Sur place; EUR 40 000 - 50 000; Plein temps

Résumé du poste

A prominent research institute in France is seeking a Post-doctoral Research Associate to apply innovative high-dimensional analysis technologies in cancer research. The role requires expertise in experimental mouse models and single-cell omics. You will contribute to profiling immune cells within the tumor microenvironment while collaborating with computational biologists. The ideal candidate holds a PhD and has a proven record in scientific publication. Competitive salary and full-time position with potential for renewal.

Qualifications

• Extensive experience with experimental mouse models in immunology or oncology context.
• Experience in current single cell omics technologies.
• Proven track record of high-level scientific achievement.

Responsabilités

• Work on immunological and molecular profiling of tissues and cells from animal models.
• Develop mechanistic insights in collaboration with computational biologists.
• Implement analytical and bioinformatics tools for data analysis.

Connaissances

Single cell RNA-seq

High dimensional flow cytometry

Spatial transcriptomics

Mouse models in immunology

Formation

PhD or equivalent

Description du poste

fixed-term contract 24 months with possibility for renewal

Organisation/Company INSERM Department Centre d'Immunologie Marseille Luminy Research Field Medical sciences » Cancer research Biological sciences » Other Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Country France Application Deadline 1 Jan 2026 - 17:00 (Europe/Amsterdam) Type of Contract Other Type of Contract Extra Information fixed-term contract 24 months with possibility for renewal Job Status Full-time Hours Per Week 36 Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are seeking a Post-doctoral Research Associate with expertise in applying state-of-the-art high-dimensional single-cell analysis technologies and spatial proteogenomics to dissect interaction networks between immune cells and the tumor microenvironment. The post holder will develop experimental work flows for data acquisition and apply bioinformatics tools to create novel analytical pipelines for analysis of multidimensional data sets. The project will involve (but not be limited to) applying sophisticated mouse genetic models of cancer and conditional gene targeting, single-cell RNA-seq, spectral flow cytometry, multiplex imaging and spatial genomics data acquisition and analysis.

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

We are seeking a highly motivated and ambitious post-doctoral research associate who is methodical, rigorous, reactive and attentive with a strong work ethic and high integrity. You will already have extensive experience with experimental mouse models in an immunology and/or oncology context. You will have experience of current single cell omics technologies including single cell RNA-seq, high dimensional flow cytometry and ideally spatial transcriptomics and/or highly multiplexed imaging. You should have a proven track record of high-level scientific achievement as evidenced by previous publications and research outputs.

Specific Requirements

Specific responsibilities:

• To work on the immunological and molecular profiling of tissues and cells from animal models of cancer.
• To develop mechanistic insights derived from such profiling activities in collaboration with computational biologists.
• To use a variety of technologies to investigate the functional immunological status of cancers and the influence of their microenvironments.
• To implement analytical and bioinformatics tools to analyse and interpret multidimensional data.
• To establish workflows for collection and analysis of samples from preclinical cancer models and develop experimental protocols.
• To support writing of grants and manuscripts for publication of scientific results.
• To promote research initiatives and original contributions to the research programmes of the team and the Centre as a whole.

General responsibilities:

• To contribute in experiment design, collection and analysis of data for the teams research projects.
• To maintain careful permanent records of all experimental work.
• To maintain appropriate databases, keeping accurate written and digital records and ensure that these records are stored securely and confidentially.
• To attend and participate in the Centre's academic activities.
• To keep up to date with scientific and professional issues, in particular developments in the specific subject area.

Languages ENGLISH Level Good

Research Field Biological sciences » BiologyMedical sciences » Cancer researchMedical sciences » Other Years of Research Experience 1 - 4

Additional Information

The Institute

The Centre d’Immunologie Marseille-Luminy (CIML) is a leading immunology focused research institute in Europe. CIML is a public research institute core funded by CNRS, INSERM and Aix-Marseille University located at the heart of the Luminy Science and Technology Park in Marseille, adjacent to the Parc National des Calanques bordering the Mediterranean coastline in southern France.

The Luminy campus is science an biotechnology hub combining life science teaching for Aix-Marseille University, various research institutes, biotech companies and leisure facilities.

The CIML ( http://www.ciml.univ-mrs.fr/ ) is home to 185 scientists, students and post-docs split into 15 research groups covering diverse aspects of immunology, including 7 ERC laureates. CIML provides state-of-the-art core facilities including advanced flow cytometry, bioimaging, genomics, mouse transgenics, CRISPR/CAS9 screening and computational biology platforms in a dedicated research building. The CIML is a highly collegial and diverse institute represented by 27 different nationalities, including 5 of the Centre’s 15 team leaders coming from outside France.

The Team

The Lawrence lab is focused on the immunobiology of macrophages and dendritic cells and in particular their roles in cancer. Projects in the lab aim to dissect the mechanisms controlling the dynamics and functional polarisation of tumor associated macrophages and dendritic cells using genetically modified mouse models and conditional gene targeting. This project, supported by the Wellcome Trust ( https://wellcome.org/ ), will focus on resident tissue macrophages as prototypes of tissue resident immune cells and their axes of interaction with cells in the tumor-microenvironment and their impact on tumorigenesis.