Post-doctoral in Obesity and Type 2 Diabetes

euraxess.ec.europa.eu - Jobboard; France; Sur place; EUR 33 000 - 40 000; Plein temps

Résumé du poste

A leading research institution in France is seeking a motivated Postdoctoral Researcher to investigate the role of a novel regulator in obesity and type 2 diabetes. The position involves cellular and in vivo experimentation, requiring a PhD and expertise in cell biology and mammalian cell culture. Applicants should possess strong analytical and communication skills. This full-time role offers a collaborative environment within a diverse team of researchers.

Qualifications

• Experience in analysis of gene expression by RT-qPCR.
• Good communication skills in English, orally and written.
• Team-oriented personality.

Responsabilités

• Investigate the mechanisms of action of the novel regulator.
• Characterize obesity mouse model of transgenic mice.
• Perform metabolic profiling and mitochondrial function analysis.

Connaissances

Cell biology

Mammalian cell culture

Data analysis tools

Communication skills in English

Organization skills

Formation

PhD or equivalent

Outils

RT-qPCR

Western blot

Confocal microscopy

Description du poste

Organisation/Company INSERM PARIS CENTRE NORD Department 75 Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions PhD Positions Country France Application Deadline 15 Dec 2025 - 23:59 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 38h30 Offer Starting Date 2 May 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Investigate a novel regulator in obesity :

Obesity, overweight, and type 2 diabetes (T2D) are major public health concerns. Adipose tissue stores excess energy as fat and acts as an endocrine organ, releasing hormones and inflammatory molecules that influence metabolism, appetite, and insulin sensitivity. Our research focuses specifically on the function of G protein-coupled receptors (GPCRs) involved in obesity/diabetes. GPCRs are of significant therapeutic interest because they can be easily targeted by drugs. We are seeking a motivated and talented Postdoctoral Researcher to join a funded project aimed at uncovering the role of a GPCR in obesity and diabetes, using cellular and in vivo experimentation (PI: Dr. Julie DAM).

Activities main

• Investigate the mechanisms of action of the novel regulator
• Characterize obesity mouse model of transgenic mice
• Main techniques to be performed by the postdoctoral fellow: cell culture (adipocyte primary culture), western blot, RT-qPCR, cell signaling, immunoprecipitation, in vivo metabolic profiling, mitochondrial function analysis, confocal microscopy, histology
• Expertise in cell biology, mammalian cell culture
• Expertise in obesity and type 2 diabetes would be appreciated

Know-how

• Experience in analysis of gene expression by RT-qPCR, detection of protein by western-blot and by immunofluorescence
• Experience in microscopy imaging (confocal)
• Experience in basic mouse experimentation.
• Experience in primary culture of adipocytes would be appreciated

Ability

• Good communication skills in English, orally and written
• Strong organization and scientific rigor skills
• Curiosity and Motivation for scientific projects
• Ability to solve problems
• Team-oriented personality
• Strong analytical skills and experience with data analysis tools

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Specific Requirements

Job specification(s) and environment

• The team is composed of 15 international members