PhD studentship

INSERM; France; Sur place; EUR 22 000 - 30 000; Plein temps

Résumé du poste

A prominent research institution in France seeks a PhD student for a groundbreaking project on single-cell analysis technologies and spatial proteogenomics, focusing on immune cells and the tumor microenvironment. Candidates should possess a Master’s degree and experience with experimental mouse models in immunology or oncology. The role offers a fixed-term contract of 36 months, starting January 2026, and involves creating analytical pipelines for complex data sets.

Qualifications

• Highly motivated and ambitious individual with a strong work ethic and high integrity.
• Methodical, rigorous, reactive, and attentive.

Responsabilités

• Work on immunological and molecular profiling of tissues and cells from animal models of cancer.
• Develop mechanistic insights in collaboration with computational biologists.
• Use technologies to investigate functional immunological status of cancers.
• Implement bioinformatics tools to analyze multidimensional data.
• Establish workflows for sample collection and analysis.

Connaissances

Experience with experimental mouse models

Single cell RNA-seq

High dimensional flow cytometry

Spatial transcriptomics

Highly multiplexed imaging

Formation

Master Degree or equivalent

Outils

Bioinformatics tools

Analytical tools

Description du poste

fixed term contract for 36 months with possibility for extension for 12 months

Organisation/Company INSERM Department Centre d'Immunologie Marseille Luminy Research Field Medical sciences » Cancer research Medical sciences » Other Biological sciences » Biology Biological sciences » Other Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country France Application Deadline 1 Dec 2025 - 10:00 (Europe/Paris) Type of Contract Other Type of Contract Extra Information fixed term contract for 36 months with possibility for extension for 12 months Job Status Full-time Hours Per Week 36 Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are seeking a PhD student candidate for a project applying state-of-the-art high-dimensional single-cell analysis technologies and spatial proteogenomics to dissect interaction networks between immune cells and the tumor microenvironment. The post holder will develop experimental work flows for data acquisition and apply bioinformatics tools to create novel analytical pipelines for analysis of multidimensional data sets. The project will involve (but not be limited to) applying sophisticated mouse genetic models of cancer and conditional gene targeting, single-cell RNA-seq, spectral flow cytometry, multiplex imaging and spatial genomics data acquisition and analysis.

Where to apply

E-mail [e-mail]

Requirements

Research Field Biological sciences » Biology Education Level Master Degree or equivalent

Skills/Qualifications

We are seeking a highly motivated and ambitious individual who is methodical, rigorous, reactive and attentive with a strong work ethic and high integrity. You will already have experience with experimental mouse models in an immunology and/or oncology context. You will have some experience of current single cell omics technologies including single cell RNA-seq, high dimensional flow cytometry and ideally spatial transcriptomics and/or highly multiplexed imaging.

Specific Requirements

Specific responsibilities:

• To work on the immunological and molecular profiling of tissues and cells from animal models of cancer.
• To develop mechanistic insights derived from such profiling activities in collaboration with computational biologists.
• To use a variety of technologies to investigate the functional immunological status of cancers and the influence of their microenvironments.
• To implement analytical and bioinformatics tools to analyse and interpret multidimensional data.
• To establish workflows for collection and analysis of samples from preclinical cancer models and develop experimental protocols.
• To promote research initiatives and original contributions to the research programmes of the team and the Centre as a whole.

General responsibilities:

• To contribute in experiment design, collection and analysis of data for the teams research projects.
• To maintain careful permanent records of all experimental work.
• To maintain appropriate databases, keeping accurate written and digital records and ensure that these records are stored securely and confidentially.
• To attend and participate in the Centre's academic activities.
• To keep up to date with scientific and professional issues, in particular developments in the specific subject area.

Languages ENGLISH Level Good

Research Field Biological sciences » BiologyBiological sciences » OtherMedical sciences » MedicineMedical sciences » Other Years of Research Experience None