Principal Scientist, Human Genetics (African Genomics Program)

F. Hoffmann-La Roche Gruppe; Ourense; Presencial; EUR 70.000 - 120.000; Jornada completa

Descripción de la vacante

A leading healthcare company seeks a Principal Scientist in Human Genetics to leverage African genomic data for advancing biological understanding and novel therapeutic strategies. This role demands a strong statistical genetics background and significant experience in human genetics. Join a collaborative team dedicated to innovation in healthcare.

Formación

• 5-10 years experience using human genetics for disease understanding.
• Recognized leader equivalent to assistant professor at top university.
• Excellent research publication record in top-tier journals.

Responsabilidades

• Lead genomic data analysis for African populations.
• Drive innovative research strategies enhancing biological understanding.
• Collaborate with academic and clinical teams on therapeutic development.

Conocimientos

Statistical genetics

Genetic epidemiology

Computational skills

Large-scale data analysis

Causal inference

Communication

Educación

PhD in relevant field

Descripción del empleo

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come.

Creating a world where we all have more time with the people we love.

That’s what makes us Roche.

The Opportunity

Roche Africa is seeking a Principal Scientist, Human Genetics (African Genomics Program)to join our team.

Are you ready to accelerate the application of African genomics to advance biological understanding and highlight novel therapeutic and biomarker strategies? The Genentech / Roche African Genomics Program invites applications for a Principal Scientist position focused on African genomics. Join us to leverage our extensive genetic, genomic, proteomic, and clinical data repositories with a focus on unique datasets generated through the Roche African Genomics Program. Drive innovative research strategies that allow us to describe the genetic basis of disease risk and therapeutic response, and to support patient stratification. Collaborate with recognized scientific leaders in industry and academia to make breakthrough healthcare solutions a reality.

Spearhead analysis of genetic and genomic data gathered from African and African-descent populations to uncover novel biology, in close collaboration with our academic collaborators and with the human genetics and computational teams within Roche

Identify and characterize genetic disease risk, progression, and therapeutic responses in African- and African-descent populations

Utilize large-scale experimental and computational capabilities, including AI / ML, to place genetic findings in their functional context.

Implement research strategies to translate these insights into novel opportunities for therapy, prevention and diagnosis

Lead efforts in target identification, causal inference, biomarker discovery, and clinical strategies, working closely with our research and clinical development teams to prioritize and advance targets into therapeutic development.

Contribute to a collaborative community involving research biology, clinical development, translational medicine, and computational sciences teams.

Who You Are as an Ideal Candidate

You are a PhD with a strong focus on statistical genetics, genetic epidemiology, or related fields, and strong proficiency in the development and / or application of statistical methods

Strong computational skills, including large-scale data analysis and causal inference.

5-10 years of experience using human genetics to understand diseases, in academia and / or industry with a focus on association studies in ancestrally-diverse cohorts

Recognized leader in your field, equivalent to an assistant professor at a top research university.

Excellent research record with scientific publications in top-tier journals.

Passionate about leveraging emerging African data sets to solve biological questions and deliver health care advances.

Exceptional communication and interpersonal skills to present and explain findings to diverse audiences (excellent written & spoken English are essential).

Proven ability to deliver compelling external presentations

Motivated to thrive in a fast-paced, collaborative research environment

Ability to operate independently, be an active proactive problem solver and demonstrate strong critical thinking and systems awareness.

Ability to travel

Preferred

Experience forming and / or participating in consortium research efforts

Experience in industry and / or biotechnology settings and / or public health / policy

Fluency in French or Portuguese a plus

Africa-based candidates strongly preferred (location preference : Nairobi, Johannesburg / Cape Town)

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.

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