Senior Director, Engineering Design

Genmab A/S; København; On-site; DKK 1,800,000 - 3,000,000; Full time

Benefits offered by this job

Pension

Health insurance and wellness benefits

Paid time off

Employee support programs

Job summary

Genmab A/S seeks a Sr. Director, Engineering Design to lead the establishment of its first internal manufacturing site in the US. Based in Denmark, you will drive feasibility, concept, basic, and detailed design with external partners and Genmab teams, ensuring governance and timely decision‑making.

You will integrate the US site team with Genmab HQ, oversee contractor onboarding, and translate Genmab’s culture into the new site, with regular travel to the US.

Qualifications

• PhD/ MSc or equivalent in a relevant Biotech field.
• 15+ years biologics manufacturing experience in biotech/pharma.
• Leadership of large-scale CAPEX projects (>USD 100M) and site start-ups.
• Strong manufacturing IT/automation and utilities knowledge.
• Regulatory inspections experience (FDA/EMA/PMDA).

Responsibilities

• Lead feasibility to detailed design phases for the new US facility.
• Coordinate with QA, external partners, and Genmab HQ for governance.
• Establish early US site team and local processes aligned with Genmab standards.
• Ensure clear escalation, risk management, and progress visibility.
• Support contractor onboarding and governance throughout CAPEX.

Skills

Project leadership

CAPEX management

Regulatory knowledge

Cross-functional collaboration

Stakeholder management

Budgeting

Communication

Education

PhD, MSc, or equivalent in Biochemistry/Chemical Eng./Biotech

Tools

Manufacturing IT/Automation

Utilities HVAC knowledge

Process equipment

GxP/QA systems

Job description

At Genmab, we are dedicated to building extraordinary futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

The Role

In this newly created role, the Sr. Director, Engineering Design will play a critical leadership role in evaluating options and then establishing Genmab’s first internal manufacturing site in the United States, ensuring that engineering design, CAPEX execution readiness, and site establishment are advanced with clarity, pace, and strong governance.

Based in Denmark and reporting to the SVP, CMC Development and Manufacturing, the role will drive development of the feasibility, concept design, basic design, and detailed design phases for the new manufacturing facility in close collaboration with external partners and Genmab colleagues in both Denmark and the US.

The role will serve as a key integrator between the CAPEX Project Manager/Site Head based in the US, the SVP based in DK, QA and enabling functions primarily at Genmab headquarters in Denmark, ensuring aligned decision‑making, clear escalation, and shared visibility of progress for the CAPEX project and alignment with site establishment activities.

In addition, the role will support the selection and onboarding of key contractors and partners, contribute to establishing the initial US manufacturing site team, and help translate Genmab’s operating model and culture into the new manufacturing environment.

Regular travel to the US will be required.

Key Responsibilities

CAPEX Project Leadership

• Lead development of the feasibility, concept design, basic design, and detailed design phases for the manufacturing facility.
• Serve as primary reviewer, and where relevant contributor, for facility design, utilities, process equipment, manufacturing IT/automation, and related engineering design elements.
• Support selection, onboarding, and governance of key contractors and external partners in the US.
• Drive recurring project governance meetings and support steering committee preparation, follow‑up, and decision tracking.
• Establish robust project documentation practices, including document hierarchy categorization, version discipline, and decision records.

Integration Between US Site Team and Genmab HQ

• Act as the primary link between the SVP, the CAPEX Project Manager/Site Head, QA and enabling functions primarily at Genmab headquarters in Denmark.
• Ensure the SVP and CAPEX Project Manager/Site Head have a shared, current view of progress, risks, decisions for the CAPEX project and dependencies in relation to site establishment.
• Facilitate timely escalation and resolution of issues requiring executive alignment or cross‑functional input.

Establishment of Initial Site Team

• Collaborate with the SVP, CAPEX Project Manager/Site Head, QA and enabling functions to establish the initial team at the US manufacturing site.
• Support development of local processes, procedures, and ways of working aligned with Genmab’s standards and future operational needs.
• Help embed Genmab’s culture, collaboration model, and quality mindset into the new site as the organization scales.

Required Qualifications

Education

• PhD, MSc, or equivalent degree in Biochemistry, Chemical Engineering, Biotechnology, or a related discipline.

Experience

• 15+ years of experience in biologics manufacturing within the biotech or pharmaceutical industry, including strong technical expertise in monoclonal antibody manufacturing.
• Deep process knowledge at thought‑leadership level, including upstream, downstream, conjugation, and preferably antibody‑drug conjugates and drug product filling.
• Strong understanding of manufacturing IT/automation, utilities incl. HVAC, process equipment, and site infrastructure.
• Proven experience with large‑scale CAPEX projects of more than USD 100 million, site start‑ups, and/or facility expansions, including establishing and managing user requirements.
• People leadership experience in commercial biologics manufacturing operations.
• Experience with validation concepts and process qualifications.
• Experience with regulatory inspections, including FDA, EMA, PMDA, or equivalent authorities.

Competencies

• Excellent project leadership skills with a proven ability to establish effective collaboration with external partners.
• Strong financial acumen and ability to support disciplined CAPEX decision‑making.
• Strong stakeholder management and cross‑functional collaboration capabilities.
• Excellent communication skills and ability to navigate across all organizational levels.

The proposed gross annual/hourly base salary range for this position, in the primary location, based on a full time schedule is:

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The final salary offer will depend on several factors, including your skills, qualifications, and experience.

In addition to base salary, this position is eligible for additional forms of compensation, such as discretionary bonuses and long‑term incentives.

When you join Genmab, you become a part of a culture that supports your physical, financial, social, and emotional well‑being. Our benefits include, but are not limited to:

• Pension
• Health insurance and wellness benefits
• Paid time off
• Employee support programs

Further details on eligibility for compensation and benefits based on the role will be provided during the recruitment process.

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard‑working, innovative and collaborative team has invented next‑generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T‑cell engagers, antibody‑drug conjugates, next‑generation immune checkpoint modulators and effector function‑enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock‑Your‑Socks‑Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

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