Research Assistant in Fungal Immunology - DTU Health Tech

DTU; Kongens Lyngby; In loco; DKK 357.000 - 469.000; Tempo pieno

Descrizione del lavoro

DTU Health Tech seeks a Research Assistant to contribute to a project on fungal meningitis using in vivo mouse models. You will focus on γδ T cells and innate-like lymphocytes, applying flow cytometry and single-cell RNA sequencing. Collaboration spans international partners and a dynamic, multidisciplinary team.

We value hands-on experimental work, data analysis, and mentoring junior colleagues. The position is a two-year contract within an environment that emphasizes collaboration, rigor, and

Competenze

• Two-year master’s degree or equivalent
• Experience with mouse immunology (publications or thesis)
• FELASA B certification or equivalent for mouse work in Europe
• Experience with multi-parametric flow cytometry
• Experience with isolation and culture of mouse lymphocytes
• Basic molecular biology and biochemistry skills
• Basic microbiology skills
• Analytical skills for multi-parametric flow cytometry and R
• Experience with single-cell RNA-sequencing is advantageous

Mansioni

• Organize and perform experiments and critically analyse data
• Demonstrate techniques to students and new lab members
• Present in lab and section meetings frequently
• Have frequent meetings with the group leader
• Be part of larger experiments not directly tied to this project
• Contribute to basic lab maintenance

Conoscenze

Mouse immunology

Multi-parametric flow cytometry

Molecular biology basics

Microbiology basics

R programming

Single-cell RNA-sequencing

Analytical skills for flow cytometry

Formazione

Master's degree (120 ECTS) or equivalent

Strumenti

Flow cytometry

Descrizione del lavoro

We offer a research assistant (RA) position starting between January and March 2027. The project will investigate the cellular and molecular mechanisms underpinning fungal meningitis, with a particular focus on γδ T cells as well as other subsets of innate and innate‑like lymphocytes. More specifically, we will use an in vivo mouse model of fungal meningitis to understand the importance of type 1 and type 3 γδ T cells in controlling infection.

The position is in close collaboration with Professor Rebecca Drummond at the University of Birmingham, UK, and is part of a consortium comprised additionally by Associate Professor David Meya at the Makerere University College of Health Sciences, Uganda, and by Professor Nanna MacAulay at the University of Copenhagen.

You will join a dynamic and international team that utilizes in vivo mouse work and human clinical samples to understand the development of γδ T cells and their importance in various diseases, such as cancer and inflammation. Technically, our work is heavily focused on flow cytometry and single‑cell RNA‑sequencing and as a successful candidate you are expected to be and/or become an expert in both. The team has a strong ethos of direct collaboration and you will be often asked to help with and be involved in other projects as a result of helping your colleagues.

The group is part of the Section for Experimental and Translation Immunology at the Department of Health Technology. Our section has all the necessary infrastructure and comprises of diverse teams with multiple technical and theoretical expertise.

You can read more about our section and department at Section for Experimental and Translation Immunology and Department of Health Technology.

Required qualifications:

• You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree
• Demonstrable experience (through publications or thesis work) with mouse immunology
• FELASA B certification or equivalent that licenses work with mice in Europe is necessary.
• Demonstrable experience (through publications or thesis work) with multi‑parametric flow cytometry
• Demonstrable experience (through publications or thesis work) with isolation and culture of mouse lymphocytes from various organs
• Basic skills in molecular biology and biochemistry (e.g. cloning, gene expression, protein identification)
• Basic skills in microbiology
• Analytical skills including analysis of multi‑parametric flow cytometry and experience with R
• Experience with single‑cell RNA‑sequencing, in particular analysis of data would be an advantage.

Applicable responsibilities:

• You are expected to be able to organize and perform experiments, and critically analyse data
• You are expected to demonstrate techniques in students and new members of the lab
• You will have to present in lab and section meetings frequently
• You will have frequent meetings with the group leader
• You are expected to be part of larger experiments not in direct association with this project
• You are expected to contribute to basic lab maintenance

Assessment

The assessment of the applicants will be made by the group leader Vasileios Bekiaris and senior members of the group.

We offer

DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment

The appointment will be based on the collective agreement with the Confederation of Professional Associations. Please see DTU’s salary structure for scientific staff: www.inside.dtu.dk/en/human-resources/during-employment/salary/salary-structures

The period of employment is 2 years.

You can read more about career paths at DTU here.

Further information

Further information may be obtained from Vasileios Bekiaris, [e-mail].

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open‑source background checks may be conducted on qualified candidates for the position.

DTU Health Tech

With a vision to improve health and quality of life through technology, DTU Health Tech engages in research, education, and innovation based on technical and natural science. We educate tomorrow’s health tech engineers and create the foundation for new and innovative services and technologies for the globally expanding healthcare sector with its demands for the most advanced technological solutions. DTU Health Tech’s expertise can be described through five overall research areas: Diagnostic Imaging, Digital Health, Personalised Therapy, Precision Diagnostics, and Sensory and Neural Technology. Our technologies and solutions are developed with the aim of benefiting people and creating value for society. The department has a scientific staff of about 210 persons, 140 PhD Students, and a technical/administrative support staff of about 100 persons of which a large majority contributes to our research infrastructure and related commercial activities.

DTU – For the benefit of society since 1829

DTU is one of Europe’s leading elite technical universities. Through research and education at an international top level, we create solutions to the major societal challenges of our time and help secure Europe’s global leadership in sustainable technological development. Since Hans Christian Ørsted founded DTU almost 200 years ago, our mission has remained the same: We develop and create value through the natural and technical sciences for the benefit of society. DTU has 13,800 students, 1,600 PhD students, and 6,500 employees. We work in an international environment and have an inclusive, stimulating, and informal work culture. DTU has campuses in all parts of Denmark and in Greenland and collaborates with the best universities around the world.