Principal Technologist or Associate Scientist, Assay Development

Zealand Pharma; Denmark; On-site; DKK 523,000 - 673,000; Full time

Job summary

Zealand Pharma A/S is seeking a Laboratory-based Principal Technologist or Scientist to lead assay development and qualification for peptide therapeutics. You will work in the Pharmacokinetics, Immunogenicity & Bioanalytical Sciences group, developing cell-based and ligand-binding assays, and supporting technology transfer to CROs while producing critical reagents. Strong documentation and English communication are essential.

Qualifications

• Hands-on expertise in bioanalytical techniques.
• Experience with assay development and qualification.
• Strong documentation and data analysis skills.
• Proficient English, written and spoken.

Responsibilities

• Develop and qualify cell-based and ligand binding assays.
• Support assay transfer to CROs and generate reagents.
• Maintain cell culture for assay purposes.
• Analyze data and provide comprehensive documentation.
• Collaborate across the pharmacokinetics, immunogenicity and bioanalytical sciences team.

Skills

Bioanalytical techniques

English proficiency

Documentation skills

Team collaboration

Attention to detail

Education

Laboratory technologist qualification or scientific degree

Tools

ELISA

electrochemistry

affinity chromatography

surface plasmon resonance

Job description

Principal Technologist or Associate Scientist, Assay Development

Does it excite you to work with ligand binding and cell based assay development, and do you have experience with assay design and qualification? If this sounds like you, and you are ready to take on a broad range of responsibilities, then you could be our new colleague.

Your new position

We are seeking a Laboratory-based Principal Technologist, or a scientist with an interest in lab work, to join the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. In this role, you will play a key part in developing and qualifying high-quality assays to detect our novel peptide therapeutics and characterize immunogenicity during preclinical and clinical development. You will support the development of various assays, contribute to technology transfer to contract research organizations (CROs), and generate critical reagents essential to our assay pipeline.

We offer exciting responsibilities:

• Development and qualification of cell-based and ligand binding
  immunogenicity assays (anti-drug antibodies and neutralizing antibodies)
• Support general ligand binding assay development, qualification, and
  sample analysis as required
• Production, purification, and characterization of critical reagents
• Cell culture maintenance and optimization for assay purposes
• Support assay transfer and validation to contract research organizations
  (CROs)
• Data analysis, interpretation, and comprehensive documentation

Your profile

We are looking for a dedicated and detail-oriented Laboratory-based Principal Technologist or a Scientist, with a genuine interest in lab work, a passion for assay development and analytical method science. You bring hands-on expertise in bioanalytical techniques and a strong understanding of how biomolecules behave in various analytical systems. You are a recognized technical contributor, highly motivated, and possess strong communication skills in English. You thrive in a collaborative environment and take pride in creating comprehensive documentation of your work.

• Laboratory technologist qualification (e.g., biomedical laboratory
  technology) or a scientific degree (e.g., biology, biochemistry, pharmacy)
  with a clear interest in hands-on laboratory work
• 5 to 10 years of hands-on experience in development and qualification of
  assays including immunogenicity assays, biomarker assays, and
  quantitative ligand binding assays (cell-based and ligand binding formats)
• Good understanding of various analytical techniques used for
  biomolecules (e.g., ELISA, electrochemiluminescence, affinity
  chromatography, surface plasmon resonance, or related methods)
• Thorough understanding of analytical methods for quantifying, detecting,
  and characterizing drug-induced immunogenicity
• Excellent documentation and data analysis skills
• Proven ability to master core processes independently while being an
  effective team collaborator
• Proficient in English, both written and oral communication

Your new team

The Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences - a dedicated group of specialists collaborating to understand the behavior of our drug candidates on efficacy and safety. You will work alongside experienced scientists and technologists committed to advancing high-quality bioanalytical support for our pipeline.

Let’s bond and be bold

We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. And we want you to help us strengthen this culture.

Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other. We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Join us and let’s bond and be bold.

Interested in bonding with us? Then please apply no later than October 18 , 2026, or as soon as possible. The applications will be reviewed as they come in. While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.

For further information, please contact Vice President, Pharmacokinetics, Immunogenicity & Bioanalytical Sciences, Carsten Boye Knudsen, [e-mail] / 50603614.

We are committed to an inclusive recruitment process and welcome applications from all job applicants.

About Zealand Pharma A/S

Zealand Pharma A/S (Nasdaq: ZEAL) is a biotechnology company focused on advancing medicines for obesity and metabolic health. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. To date, more than ten Zealand Pharma-invented drug candidates have entered clinical development, of which two products have reached the market and three candidates are in late-stage development. The Company has collaborations with global pharmaceutical and biotechnology partners for research, development, and commercialization. Founded in 1998, Zealand Pharma is headquartered in Copenhagen, Denmark, with a U.S. presence in Boston, Massachusetts. Learn more at www.zealandpharma.com.