Global IT Compliance Leader: GxP, SOX & Validation

Ascendis Pharma; København; On-site; DKK 1,200,000 - 1,800,000; Full time

Job summary

Ascendis Pharma is seeking a Head of IT Compliance to lead our IT compliance strategy across global operations. Based at our headquarters in Hellerup, Denmark, you will guide a team of specialists and partner with IT product and platform teams to translate regulatory requirements into pragmatic, risk-based practices.

You will shape the IT Quality Management System, monitor evolving frameworks, and champion a quality mindset, shift-left testing, and agile ways of working.

Qualifications

• You hold a relevant academic degree and bring extensive experience from regulated pharmaceutical or life-science environments, ideally including 10+ years within IT compliance, quality, validation, or related disciplines.
• You have leadership experience and can combine strategic direction with practical support to teams and stakeholders.

Responsibilities

• Lead and further develop the IT Compliance function, including setting direction, developing team capabilities, and fostering a culture of quality, learning, and critical thinking.
• Partner with IT Product and Platform teams operating in GxP-regulated environments to enable compliant, efficient, and business-focused delivery.
• Serve as a trusted advisor to leaders and stakeholders on IT compliance, quality management, computer system validation, testing, and applicable regulatory requirements.
• Drive the continuous evolution of the IT Quality Management System (IT QMS), governance frameworks, and related compliance processes, including SOX controls.
• Monitor and assess emerging regulatory requirements, ensuring that relevant changes are reflected in IT policies, standards, procedures, and ways of working.
• Promote modern compliance practices by advancing continuous compliance principles, shift-left testing approaches, and agile methodologies across Global IT.
• Build compliance capabilities across the organization through training, coaching, knowledge sharing, and awareness initiatives

Skills

GxP compliance

SOX controls

computer system validation

regulatory frameworks

leadership

quality management

risk-based approach

Education

Bachelor's degree in a relevant field

Job description

Ascendis Pharma is seeking a Head of IT Compliance to lead our IT compliance strategy across global operations. Based at our headquarters in Hellerup, Denmark, you will guide a team of specialists and partner with IT product and platform teams to translate regulatory requirements into pragmatic, risk-based practices.

You will shape the IT Quality Management System, monitor evolving frameworks, and champion a quality mindset, shift-left testing, and agile ways of working.