Computational Postdoc: Mammalian Metabolic Design

Danmarks Tekniske Universitet; Ørsted; On-site; DKK 480,000 - 600,000; Full time

Job summary

DTU Bioengineering in Lyngby, Denmark seeks a computational postdoctoral researcher to design next-generation mammalian cell lines for biotherapeutic production. You will drive in silico pathway design and integrate multi-omics data to guide experimental engineering and reduce production costs.

You will lead manuscript preparation, present at international conferences, and mentor students; a PhD is required and excellent English communication is essential.

Qualifications

• Experience with mammalian genome-scale metabolic models and constraint-based modeling (e.g., COBRApy).
• Proficiency in multi-omics data analysis to extract actionable biological insights.
• Experience with structural bioinformatics, molecular docking, or cheminformatics for predicting protein interactions.
• Strong programming skills (Python, R) and familiarity with Git.
• Evidence of high-impact publications with first-author status.
• Excellent English communication for interdisciplinary audiences.
• Experience mentoring PhD/MSc/BSc students in mammalian cell culture and genetic engineering.

Responsibilities

• Pathway design and metabolic modeling using genome-scale models; integrate experimental data to refine targets.
• Multiomic target discovery to identify bottlenecks and engineering targets.
• Model protein-metabolite interactions and assess inhibitory interactions.
• Lead manuscript preparation and present findings at international conferences.
• Mentor PhD, MSc, and BSc students in the group.

Skills

Mammalian GEMs

Multi-omics analysis

Protein-ligand interactions

Programming (Python, R)

First-author publications

English communication

Mentoring

Mammalian cell culture

Education

PhD degree

Tools

COBRApy

Git

Job description

DTU Bioengineering in Lyngby, Denmark seeks a computational postdoctoral researcher to design next-generation mammalian cell lines for biotherapeutic production. You will drive in silico pathway design and integrate multi-omics data to guide experimental engineering and reduce production costs.

You will lead manuscript preparation, present at international conferences, and mentor students; a PhD is required and excellent English communication is essential.