Advanced Mass Spectrometry Research Position

The University of Applied Sciences and Arts Western Switzerland Valais (HES-SO Valais-Wallis) is a leading institution in education and research, with over 2,800 students.

Through innovation and collaboration, it contributes to the development of the region and the creation of jobs.

This unique opportunity offers a researcher position in an academic / industrial setting, focusing on advanced research in mass spectrometry-based biotherapeutic profiling.

Key Responsibilities :

• Perform LC-HRMS-based proteomics workflows, focusing on Orbitrap instruments.
• Design and execute sample preparation protocols.
• Process, interpret, and report data for proteomics and biotherapeutic characterisation projects.
• Apply and optimise MAM strategies for detailed characterisation of biologics.
• Analyse host cell protein profiles for quality and process control.
• Collaborate with software developers to streamline data processing and integration.
• Engage with industry stakeholders to translate findings into real-world applications.
• Contribute to manuscript preparation, reports, and scientific presentations.

Required Skills and Qualifications :

• PhD in Analytical Chemistry, Biochemistry, or a related field.
• Demonstrated expertise in LC-HRMS, particularly with Orbitrap mass spectrometers.
• Experience with proteomics workflows, including digestion, enrichment, and quantification techniques.
• Expertise with Genedata Expressionist or similar proteomics data analysis platforms; knowledge of MAM workflows and HCP analysis will be considered a valuable asset.
• Knowledge of protein structure, post-translational modifications, and therapeutic protein analysis.
• Experience with bioinformatics and / or coding in R, Python, or similar languages is a plus.
• Strong organisational, communication, and collaborative skills.
• Proficiency in spoken and written English is required.