Senior Toxicologist, Non-Clinical Pharmacology Leader

Sobi; Basel; On-site; CHF 140,000 - 200,000; Full time

Job summary

Sobi is seeking a Senior Toxicologist, Non-Clinical Pharmacology Scientist to lead toxicology and non-clinical pharmacology activities within PDTM. Open to Europe, with responsibilities across project stages and regulatory interactions.

The role focuses on defining strategies, managing studies with CROs, and ensuring translational safety considerations are integrated into development programs. English fluency and proactive collaboration are essential.

Qualifications

• PhD, DVM or equivalent in a relevant discipline.
• Minimum five years of experience as a project toxicologist.
• Experience with biologics and small molecules; oligonucleotides or gene therapy a plus.
• Board certification such as a DABT/ERT is a plus.
• Extensive regulatory toxicology experience and knowledge of drug development.
• Excellent communication and English language skills.

Responsibilities

• Define strategies for Toxicology and Non-Clinical Pharmacology in projects.
• Accountability for Toxicology strategies in assigned projects.
• Provide expert toxicology knowledge to cross-functional teams.
• Prepare non-clinical pharmacology sections for regulatory documents.
• Interface with regulatory authorities on non-clinical pharmacology questions.
• Manage preclinical safety studies at CROs; discuss and report findings.
• Incorporate translational safety insights and communicate safety signals.
• Perform toxicity assessments for impurities in drug products.
• Contribute to internal/external scientific communications.

Skills

Communication skills

English fluency

Problem solving

Team work

Initiative

Education

PhD or DVM in relevant discipline

Job description

Sobi is seeking a Senior Toxicologist, Non-Clinical Pharmacology Scientist to lead toxicology and non-clinical pharmacology activities within PDTM. Open to Europe, with responsibilities across project stages and regulatory interactions.

The role focuses on defining strategies, managing studies with CROs, and ensuring translational safety considerations are integrated into development programs. English fluency and proactive collaboration are essential.