Senior Statistician

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 140.000 - 210.000; Vollzeit

Zusammenfassung

Roche seeks a Senior Statistician in Basel to apply advanced statistics to the design, analysis, and interpretation of clinical trials within a cross-functional team.

You will ensure regulatory compliance, lead statistical contributions to reports, and mentor junior statisticians while partnering with development and data-science teams. This is a hands-on role in a global organization committed to scientific rigor and patient impact.

Qualifikationen

• MSc or PhD in Statistics/Biostatistics required.
• Minimum 3 years of relevant clinical trial statistics experience.
• Proficiency in SAS and/or R; familiarity with CDISC standards.

Aufgaben

• Lead statistical input into clinical trial design and document development.
• Design, conduct, and review complex analyses and interpretation of results.
• Collaborate with cross-functional teams to align deliverables and timelines.
• Contribute statistics to CSRs and regulatory documents.
• Provide mentorship to less experienced statisticians.

Kenntnisse

SAS

R

Clinical trial statistics

Regulatory knowledge

Cross-functional collaboration

Ausbildung

MSc or PhD in Statistics/ Biostatistics

Tools

SAS

R

CDISC standards

Jobbeschreibung

The Position

This role is within Biostatistics, a core function within Product Development Data Science and Analytics (PDD) that provides strategic leadership and scientific rigor across Development at Roche. Biostatistics identifies opportunities to apply the full breadth of data, digital, and design capabilities to deploy innovative methods across PDD, PD and the broader Roche Pharma organization. As trusted analytical partners in end-to-end drug development, Biostatistics leverages data to drive scientifically rigorous programmatic decisions across Roche's Development portfolio; Biostatistics designs robust trials and analysis plans that increase the probability of technical success, accelerating timelines to advance Roche's clinical pipeline and promote regulatory success — ultimately bringing medicines to our patients faster.

The Opportunity

The Senior Statistician is a key member of the cross-functional study or molecule team, responsible for applying statistical expertise to the design, conduct, analysis, and interpretation of individual clinical trials. This role ensures the scientific rigor and regulatory compliance of the study by contributing to protocol development, authoring statistical analysis plans, performing or overseeing data analyses, and supporting the interpretation and communication of results. The Statistician plays a critical role in ensuring that each study generates robust, meaningful data to support decision-making and regulatory submissions.

• You independently lead statistical input into clinical trial design, aligning with scientific objectives and own the development and quality review of statistical study documents.
• You design and execute complex analyses, proactively resolving challenges and represent Biostatistics and PDD at the Study Team level, ensuring statistical and scientific rigor of study deliverables.
• You collaborate proactively with cross-functional teams to align deliverables and timelines and interpret and communicate results in context, influencing study-level decisions.
• You lead statistical contributions to CSRs and selected regulatory documents.
• You provide functional guidance and informal mentoring to less experienced statisticians and may lead or influence study-level projects or contribute significantly to large project teams or initiatives.

Who You Are

• You hold an MSc or PhD in Statistics, Biostatistics, or a closely related quantitative field and have a minimum of 3 years of relevant experience in clinical trial statistics within a pharmaceutical, biotech, or CRO setting.
• You have demonstrated experience contributing to the design, analysis, and interpretation of clinical studies across different phases and have a solid understanding of regulatory expectations and statistical methodologies for clinical development.
• You are proficient in SAS and/or R and familiar with CDISC standards.
• You are able to work autonomously while collaborating effectively in cross-functional teams and demonstrate capacity for independent thinking and ability to make decisions based upon sound principles.
• You bring excellent strategic agility including problem-solving and critical thinking skills, and agility that extends beyond the technical domain and demonstrate respect for cultural differences when interacting with colleagues in the global workplace.
• You have excellent verbal and written communication skills, specifically in the areas of presentation and writing, with the ability to explain complex technical concepts in clear language.

Preferred

• Experience working in cross-functional global study teams and effective communication skills with the ability to translate complex statistical concepts for non-statistical audiences.
• Experience with multiple phases of drug development (early and/or late stage) and experience in mentoring or scientific leadership within a matrix organization.
• Strategic mindset with the ability to contribute to portfolio-level decisions.

This position is based in Basel and relocation assistance is not available.

Who we are

A healthier future drives us to innovate. Together, more than 100000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it's urgent to deliver medical solutions right now — even as we develop innovations for the future. We are passionate about transforming patients' lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.