Senior Director, Clinical Excellence Leader

Alentis Therapeutics; Allschwil; On-site; CHF 250,000 - 380,000; Full time

Job summary

Alentis Therapeutics seeks a Senior Director, Clinical Excellence Leader to shape and advance clinical development best practices across the organization. The role will harmonize processes, drive operational excellence in trial execution, and help build a high-performance clinical development organization.

You will collaborate with Clinical Operations, Regulatory Affairs, Biometrics, and Quality Assurance to optimize study design and execution, lead risk management, and mentor teams in a

Qualifications

• Master's degree or equivalent in Life Sciences, Healthcare, Pharmacy, or related field.
• 15+ years in clinical science and operational roles, incl. early-phase development.
• Experience in biotech and global drug development environments.
• Proven global clinical trial leadership, data review, risk management.
• Strong oncology drug development understanding.
• Experience leading cross-functional teams and people leadership is a plus.
• Excellent stakeholder management and communication skills.

Responsibilities

• Lead harmonization of cross-study practices to elevate quality and productivity.
• Develop, align, implement, and improve cross-functional clinical development processes and standards.
• Lead planning, execution, and delivery of complex global trials with timelines and budgets.
• Identify operational risks and implement mitigation strategies.
• Foster excellence, collaboration, accountability, and continuous improvement.
• Partner with Clinical Operations, Clinical Science, Biometrics, Regulatory, QA, and others to optimize study execution.
• Support capability building, knowledge sharing, and scalable processes.

Skills

Leadership

Clinical development

Cross-functional collaboration

Regulatory knowledge

Operational excellence

Project management

Communication

Education

Master's degree in Life Sciences or related field

Job description

About this position

The Senior Director, Clinical Excellence Leader will play a critical leadership role in shaping and advancing clinical development best practices across the organization. This individual will drive harmonization of processes and standards across programs, ensure operational excellence in clinical trial execution, and support the development of a high-performance clinical development organization. The role requires deep expertise in global clinical development, strong leadership capabilities, and the ability to influence stakeholders across functions and levels.

Your tasks:

• Lead harmonization of cross-study fit-for-purpose practices across development programs to elevate the quality and productivity of deliverables.

• Drive the development, alignment, implementation, and continuous improvement of cross-functional clinical development processes and standards.

• Serve as a role model and subject matter expert in the planning, execution, and delivery of complex global clinical trials, ensuring adherence to timelines, budgets, quality expectations, and regulatory requirements.

• Identify operational risks and implement proactive mitigation strategies to support program success.

• Foster a culture of excellence, collaboration, accountability, and continuous improvement across clinical development teams.

• Partner closely with Clinical Operations, Clinical Science, Clinical Development, Biometrics, Regulatory Affairs, Quality Assurance, and other internal partners to optimize study execution and decision-making.

• Contribute to organizational growth by supporting capability building, knowledge sharing, and process scalability.

Role requirements

• Master's degree or equivalent university degree in Life Sciences, Healthcare, Pharmacy, or a related field.

• Minimum of 15 years of clinical science and operational experience, including experience in early-phase clinical development.

• Experience gained in both biotechnology companies and global drug development environments.

• Demonstrated expertise in global clinical trial leadership, clinical data review and signal detection, project management, and risk management.

• Strong understanding of the oncology drug development continuum from First-in-Human (FIH) through late-stage clinical development.

• Proven ability to lead, influence, and align cross-functional teams in a dynamic environment.

• Previous people leadership experience is advantageous.

• Excellent communication, stakeholder management, and organizational skills.

• Ability to thrive in a fast-paced, entrepreneurial, and rapidly evolving biotechnology environment.

Work permit

Candidate needs to hold a Swiss work permit or be an EU citizen eligible to work in Switzerland.