Postdoctoral Position for Synthetic Biology-Inspired Therapies 100%

ETH Zurich; Basel; On-site; CHF 90,000 - 120,000; Full time

Benefits offered by this job

Public transport season tickets

Car sharing

Childcare

Pension benefits

Job summary

ETH Zurich's Biotechnology and Bioengineering group at D-BSSE in Basel invites exceptional candidates to apply for a postdoctoral position aimed at developing synthetic biology-inspired human therapies. The role focuses on molecular engineering, cell programming, and programmable cellular devices in translational research.

You will work in a highly interdisciplinary environment with molecular biologists, bioengineers, and clinical researchers, advancing bench science toward clinically relevant

Qualifications

• Strong skills in molecular and cell biology techniques
• Experience with cultivation/engineering of primary human cells and mammalian cell lines
• FELASA/LTK or equivalent course is an asset

Responsibilities

• Combine molecular engineering, cell programming, and chemical-biological interfacing to engineer human cells using synthetic gene circuits and biosensing platforms
• Develop novel biosensing systems for real-time monitoring of cellular states
• Translate research advances into programmable cellular implant prototypes and collaborate with clinical researchers

Skills

Molecular biology

Cell biology

Primary human cells

Mammalian cell lines

In vivo techniques

FELASA course

Education

PhD in biology or related field

Job description

A World-Class Research Environment at the Nexus of Biology, Engineering, and Physical Sciences

The Biotechnology and Bioengineering group led by Prof. Dr. Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel invites exceptional candidates to apply for a postdoctoral position in pioneering projects developing synthetic biology-inspired human therapies.

The D-BSSE is the first truly interdisciplinary research department, uniting theoretical and experimental biology with advanced bioengineering and fostering close collaborations with leaders in material science, physics, and chemistry to drive transformative advances in systems biology, biotechnology, and synthetic biology. Situated in Basel, Switzerland, at the heart of the BioValley, a tri-national region that hosts 40% of the global life science industry and numerous major pharmaceutical companies, the D-BSSE offers a unique environment for high-impact translational research with unparalleled access to academic and industrial expertise.

Project background

Advancing the Frontiers of Cell-based therapies and Synthetic Biology

Job description

• Postdoctoral projects will combine molecular engineering, cell programming, and chemical-biological interfacing to engineer human cells using synthetic gene circuits and biosensing platforms, develop novel biosensing systems for real-time monitoring of cellular states, create genetic architectures for precise therapeutic protein regulation, and translate these research advances into programmable cellular implant prototypes


• Projects will be highly interdisciplinary, fostering close collaboration with molecular biologists, bioengineers, and clinical researchers to accelerate translation into clinically relevant therapies

Profile

• We are seeking highly motivated applicants eager to bridge basic and translational research in cell biology and synthetic biology


• Candidates should have strong skills in molecular and cell biology techniques, including cultivation and engineering of primary human cells and mammalian cell lines


• Experience with in vivo techniques, as well as completion of an accredited course in laboratory animal science (FELASA / LTK or equivalent), would be an asset


• We welcome applicants with a strong publication record and the ambition to pursue a career in academia, industrial R&D, or biotechnology entrepreneurship

We offer

• Your job with impact: Become part of ETH Zurich, which not only supports your professional development, but also actively contributes to positive change in society


• We are actively committed to a sustainable and climate-neutral university


• You can expect numerous benefits, such as public transport season tickets and car sharing, a wide range of sports offered by the ASVZ, childcare and attractive pension benefits

We value diversity and sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us - we are consistently working towards a climate-neutral future.

Curious? So are we.

Working, teaching and research at ETH Zurich

• CV


• A list of publications


• A motivation letter


• Three letters of recommendation


• A brief research plan (1 page)

Further information about [Department/Institute] can be found on our Website or in our published work.

Questions regarding the position should be directed to Professor Martin Fussenegger, [e-mail].