Medical Director

Granite Bio; Basel; Hybrid; CHF 150.000 - 190.000; Vollzeit

Benefits dieser Stelle

Prime Location

Commuter Benefits

Flexible Working

24 days annual leave

Your Birthday Off

Coffee & Connection

Personal Development

Creative Environment

Diverse Team

Team Events

Zusammenfassung

Granite Bio in Basel seeks a physician-scientist to lead design, execution and reporting of Phase 1/2 clinical trials in immunology and inflammation. You will contribute to medical strategy, develop protocols and safety plans, and ensure data quality per GCP/SOPs.

You will collaborate with cross-functional teams, prepare statistical analyses, and author key clinical documents, driving development programs forward in a dynamic biotech environment.

Qualifikationen

• MD or equivalent required with 3+ years in clinical research.
• Strong knowledge of GCP/GLP and regulatory requirements.
• Excellent written and verbal communication skills.

Aufgaben

• Design, execute and report Phase 1/2 clinical trials in I&I space.
• Contribute to the medical team and clinical development strategy.
• Provide guidance in development of trial protocols and supporting documents (ICF, IB, SoA, TPP, SAP).
• Ensure safety and efficacy data are generated according to GCP/SOPs.
• Perform medical monitoring and oversee study progress with cross-functional teams.
• Develop and interpret statistical analysis plans and communicate results.
• Author protocols, amendments and safety plans for clinical studies.
• Collaborate with Clinical Operations and Biomarker teams to achieve milestones.

Kenntnisse

Clinical research

GCP/GLP

Regulatory compliance

Communication skills

Data analysis

Ausbildung

MD or equivalent

Jobbeschreibung

About us

GRANITE BIO is a private biotechnology company located in Basel (Switzerland). It is supported by top‑tier investors with approximately $100M raised to date. Building on fundamental research conducted over the last two decades, GRANITE BIO pursues a differentiated approach to transform inflammatory, autoimmune and fibrotic conditions. Both programs are first‑in‑class monoclonal antibodies for large market opportunities in Immunology and Inflammation. GRT‑001, the lead asset, depletes inflammatory monocytes and has completed a Phase 1a trial in healthy volunteers with favorable safety and pharmacodynamic effects; a Phase 1b trial in patients with Ulcerative Colitis has just started. GRT‑002 is an IL‑3 neutralising antibody thought to play an important role in type II inflammation. The company fosters an open, inter‑disciplinary, diverse, international and creative working environment and enables work‑from‑home options according to its internal workflows. Candidates will be highly motivated, enthusiastic with a positive “can do” attitude, attention to detail and innovation, and strong organisational and communication skills.

Responsibilities

• Design, execute, conduct and report Phase 1/2 clinical trials in I&I space.
• Contribute to the medical team and clinical development strategy.
• Provide guidance and expertise in the development of clinical trial protocols and supporting documents such as ICF, IB, SoA, TPP, SAP, etc.
• Ensure safety and efficacy data are generated and analysed according to GCP/SOPs, corporate strategy and timelines.
• Perform medical monitoring activities – oversee the study, answer eligibility questions, review safety and adverse event data, oversee coding activities.
• Work closely with cross‑functional team members to ensure planning and execution of clinical trials to meet key milestones.
• Play a key role in developing the statistical analysis plan, reviewing, interpreting and communicating clinical trial data.
• Author and develop clinical documents such as study protocols, amendments, safety management plans and medical monitoring plans.
• Collaborate with Clinical Operations and Clinical Biomarker departments to deliver clinical study programme goals and milestones.

Qualifications

• Advanced medical degree (MD or equivalent).
• At least 3 years of experience in clinical research or development within the pharmaceutical or biotechnology industry, ideally with exposure to early clinical trials.
• Strong ability to build collaborative relationships with physicians, expert consultants and external vendors.
• Strong analytical mindset with excellent written and verbal communication skills.
• Exceptional attention to detail, sound judgement and organisational skills.
• Solid knowledge of clinical trial methodology and regulatory/compliance requirements.
• Good understanding of GCP, GLP and clinical study design.
• Understanding of the framework and complexities of early multi‑centre trials, including CRO and CDO collaboration.
• Ideally, experience in autoimmune disease and/or IBD/inflammation and immunology space.
• Effective, transparent, strategic communicator.
• Team player with strong listening skills.
• Comfortable working in a dynamic, fit‑for‑purpose biotech environment.
• Proactive, solution‑oriented, thriving in ambiguous settings.
• Strong planning, organisational, and problem‑solving skills to support efficient operational execution of programmes, studies and related projects.
• Enjoys contributing to diverse teams, whether leading or as a member.
• Talented, proactive and passionate medical professional inspired to bring innovation to patients with unmet medical needs.

What we currently offer

• Prime Location – modern laboratories and offices in Tech Park Basel, a hub for early‑stage start‑ups.
• Commuter Benefits – parking options or a commuter allowance.
• Flexible Working – flexible arrangements where possible.
• Additional Time Off – 24 days of annual leave and office closure between Christmas and New Year.
• Your Birthday Off – an extra day off to celebrate your birthday.
• Coffee & Connection – free coffee and a great space to connect with colleagues.
• Personal Development – support for professional and personal growth.
• Creative Environment – work in an innovative, dynamic and creative setting.
• Diverse Team – an international team of passionate and talented people.
• Team Events – regular off‑site summer and winter events to connect and have fun together.

Please note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement.