Lead Chemical Process R+D Scientist (m/f/d)

Work Selection AG; Basel; On-site; CHF 120,000 - 160,000; Full time

Benefits offered by this job

On-site parking

Mitarbeiterrestaurant

Weiterbildung

Gleitzeit

Job summary

Work Selection AG sucht eine führende Persönlichkeit für das Bereich Chemical Process RundD zur temporären Besetzung von 12 Monaten mit Aussicht auf Verlängerung in Basel. Sie leiten interne sowie CDMO-Aktivitäten rund um chemische Prozess-RundD, skalieren Prozesse und unterstützen API-Entwicklungen.

Ideale Kandidatin oder Kandidat besitzt einen PhD/Postdoc in Synthetischer Organischer Chemie, umfangreiche Erfahrung in späten Entwicklungsphasen, Leadership-Qualitäten und Exzellenz in

Qualifications

• PhD oder Postdoc in synthetischer organischer Chemie.
• 5+ Jahre Erfahrung in pharmazeutischem chemical process R&D, mit Fokus auf späte Entwicklungsphasen und Scale-up.
• Nachweis von Leadership, Mentoring und Projektlieferung innerhalb interner Prozesschemie-Teams.
• Direkte Erfahrung im CDMO-Management, Technologietransfer und Herstellung bei CDMOs.
• Hohe Kompetenz in Standard-Office-Anwendungen sowie chemischen Zeichnungswerkzeugen und DoE- Anwendungen.

Responsibilities

• Leitung interner und externer Chemical Process RundD Aktivitäten, Teamführung von 1–5 Prozesschemikern oder Koordination von CDMO-Aktivitäten.
• Überwachung von End-to-End-Prozesschemie-Workflows, Syntheserouten-Scouting, Optimierung, Scale-up und Produktionsunterstützung.
• Koordination mit CDMOs und internen Laboren, um sichere, termingerechte und kosteneffiziente Produktion von APIs und Vorstufen sicherzustellen.
• Sicherstellung von Qualität und Compliance gemäß internen Standards, Spezifikationen, Sicherheits- und Nachhaltigkeitszielen.

Skills

Leadership

Projektmanagement

Chemische RundD

CDMO-Management

DoE-Tools

Englisch

Education

PhD oder Postdoc in synthetischer organischer Chemie

Tools

ChemDraw

Literatur-/Patentsuche

DoE-Software

Analytische Software

Skalierungssimulation

Job description

As a first-tier supplier to our renowned business partner F. Hoffmann-La Roche Ltd. in Basel, we are currently looking for a motivated and dedicated Lead Chemical Process RundD Scientist for a temporary assignment of 12 months, with high probability of extension. In this function you will lead chemical process RundD activities to deliver safe, scalable, efficient and sustainable processes as well as drug substance material for projects in clinical development, with a focus on late stage development, leveraging internal and external CDMO capabilities.

Tasks und Responsibilities

• Lead Internal und External Chemical Process RundD activities: Direct chemical process research and development work, managing an internal team of 1-5 process chemists and/or leading external activities at contract development and manufacturing organizations (CDMOs).
• Oversee end-to-end process chemistry workflows, including synthetic route scouting, process optimization, scale-up, and support for supply activities.
• Coordinate Cross-Functional Delivery: Synchronize internal laboratory efforts with CDMO timelines to guarantee the timely, safe, and cost-effective production of active pharmaceutical ingredients (APIs) and advanced intermediates
• Ensure Quality und Compliance: Deliver the target compounds following internal quality processes and according to specifications, safety standards and sustainability objectives.

Must-Haves

• PhD or Postdoctoral background in Synthetic Organic Chemistry.
• 5+ years of hands-on experience in pharmaceutical chemical process RundD, with demonstrated expertise in late-stage process development and scale-up.
• Leadership und Project Management: Proven track record of leading, mentoring, and driving project deliverables within internal process chemistry teams.
• CDMO Management: Direct experience managing external chemical development, technology transfers, and manufacturing activities at CDMOs.
• Technical und Software Proficiency: High proficiency with standard office applications alongside core chemistry tools, including chemical drawing tools, literature/patent search engines, Design of Experiments (DoE) applications, analytical software, and project planning platforms. Proficiency in the use of kinetic modeling or scale-up simulation software is a plus.
• Professional fluency in spoken and written English is required.

Benefits

• Become part of one of the most prestigious pharmaceutical companies and actively shape the future of healthcare
• Experience a work culture that promotes diversity and inclusion and where all employees feel valued.
• Work on a state-of-the- art campus featuring green spaces, meeting areas, and an inspiring atmosphere
• Work with modern and up-to-date tools in an innovative work environment
• Start with a professional onboarding process and a thorough introduction to your new role during the Welcome Days
• Benefit from financial support for your professional development plans
• Enjoy a selection of high-quality meals in modern staff restaurants
• As part of a sustainable mobility concept, on-site parking spaces are available to you (subject to eligibility criteria)
• Take advantage of unbeatable, year-round discounts at renowned retailers and over 200 top brands
• Benefit from fleet discounts when purchasing new cars or receive constant fuel discounts with our fuel card

Wir wertschätzen Vielfalt und begrüssen daher alle Bewerbungen – unabhängig von Geschlecht, sozialer Herkunft, Religion, Alter und Identität. Zur leichteren Lesbarkeit und besseren Verständlichkeit verwenden wir nur eine Gender-Form. Selbstverständlich sind im jeweiligen Kontext alle Genderformen gleichermassen gemeint.