In Vivo Radioligand Therapy Pharmacology Scientist

Novartis AG; Basel-Stadt; On-site; CHF 76,000 - 142,000; Full time

Benefits offered by this job

Hybrid working options

Parental leave 14 weeks

Comprehensive benefits

Job summary

Novartis AG in Basel, Switzerland seeks a scientist to develop and characterize in vivo oncology models to support preclinical radioligand therapy research. This onsite role requires hands-on experience with rodent models, imaging, and safety with radioactive sources.

You will perform biodistribution and pharmacology studies, conduct PET/SPECT/CT imaging, and contribute to in vitro/ex vivo work across interdisciplinary teams.

Qualifications

• Bachelor's or Master's degree in Cell Biology, Medical Physics, Bioengineering, Biotechnology, Pharmacology, or a related field.
• Hands-on experience with rodent handling and in vivo oncology models, including dosing, sampling, and animal welfare requirements.
• Practical in vivo experience gained within an academic or industry biomedical research laboratory.
• Training and practical experience working safely with open radioactive sources.
• Advanced written and spoken English, with the ability to communicate scientific findings effectively.

Responsibilities

• Develop and characterize novel in vivo oncology models to support preclinical radioligand therapy research.
• Conduct efficacy studies evaluating novel radioligand therapies across oncology programs.
• Perform biodistribution studies and metabolite analyses to inform pharmacology decisions.
• Conduct small-animal PET, SPECT, and CT imaging studies.
• Support in vitro and ex vivo activities, including cell culture, flow cytometry, immunohistochemistry, immunofluorescence, autoradiography, PCR, and Western blotting.

Skills

Rodent handling & in vivo models

In vivo pharmacology

Dosing & sampling

Open radioactivity safety

English proficiency

Education

Bachelor's or Master's in a biomedical field

Tools

PET/SPECT/CT imaging

Flow cytometry

Immunohistochemistry

Autoradiography

Job description

Novartis AG in Basel, Switzerland seeks a scientist to develop and characterize in vivo oncology models to support preclinical radioligand therapy research. This onsite role requires hands-on experience with rodent models, imaging, and safety with radioactive sources.

You will perform biodistribution and pharmacology studies, conduct PET/SPECT/CT imaging, and contribute to in vitro/ex vivo work across interdisciplinary teams.