Clinical Science Lead

CHE - 8036 Takeda Pharmaceuticals International AG; Glattbrugg; On-site; CHF 177,000 - 244,000; Full time

Job summary

Takeda Pharmaceutical Co. in Zurich, Switzerland, seeks a Director-level leader to shape scientific and operational strategy for clinical studies across interventional and non-interventional programs, including Phase 3B, Phase 4, and real-world evidence initiatives.

You will lead design, execution, governance, and reporting, ensure quality and compliance, manage budgets and timelines, and collaborate across functions to enable evidence-based decisions using AI-enabled tools.

Qualifications

• Advanced degree in a scientific, clinical, epidemiologic, quantitative, or health-related discipline.
• 10+ years of experience in clinical development and evidence generation, including interventional and non-interventional studies.
• Experience authoring protocols, study concepts, and related documentation across global studies.
• Experience leading multi-country trials, with strong knowledge of GCP, regulations, and quality standards.

Responsibilities

• Provide scientific and operational leadership for planning, implementation, and reporting of clinical and real-world studies.
• Lead study design and documentation through protocols, amendments, and related materials.
• Ensure study quality and feasibility, aligning designs with priorities and stakeholder needs.
• Oversee timelines, enrollment, budgets, risks, and quality indicators for study delivery.
• Translate clinical findings into recommendations, reports, and decision-support materials.
• Partner to support compliant governance, vendor oversight, contracting, reporting, and archiving.
• Lead vendor and external partnerships, maintaining budget stewardship.
• Drive innovation using digital and AI-enabled tools in a regulated environment.

Skills

Clinical development leadership

Real-world evidence

Study governance

Cross-functional leadership

Vendor oversight

Digital tools

Education

Advanced degree in scientific field

Job description

About the Role

In this Director level role, you will help shape the scientific and operational strategy for clinical studies across a diverse evidence generation portfolio. You will play a key role in advancing Phase 3B and Phase 4 interventional and non-interventional studies, real-world evidence initiatives, collaborative research, and investigator-initiated activities. Working across functions, you will help ensure studies are scientifically robust, operationally feasible, and delivered with a strong focus on quality, compliance, and business priorities. You will be part of a team that supports evidence-based decision-making while advancing efficient, scalable, and digitally enabled approaches to clinical research. Your work will contribute to the successful design, implementation, governance, and delivery of studies that generate meaningful evidence and support organizational goals, while promoting the appropriate use of digital and artificial intelligence-enabled tools to strengthen planning, oversight, analytics, and decision-making.

How You Will Contribute

Provide scientific and operational leadership for the planning, implementation, oversight, execution, and reporting of clinical, real-world evidence, and externally sponsored studies.

Lead study design and document development through the creation, review, and approval of protocols, amendments, study concepts, and related materials.

Ensure study quality and feasibility by aligning study designs and execution plans with evidence generation priorities and stakeholder needs.

Manage study delivery and performance by overseeing timelines, enrollment, budgets, operational metrics, risks, and quality indicators.

Interpret and communicate clinical findings by translating complex clinical and safety data into recommendations, reports, publications, and decision-support materials.

Partner across functional teams to support compliant study governance, vendor oversight, contracting, reporting, and archiving activities.

Lead vendor and external partnership management while maintaining budget stewardship across the assigned portfolio.

Drive continuous improvement and innovation through the adoption of digital and artificial intelligence-enabled tools that enhance evidence generation and study management.

Qualifications

Advanced degree in a scientific, clinical, epidemiologic, quantitative, or health-related discipline.

10+ years of experience in clinical development, evidence generation, clinical research, or related disciplines involving interventional and non-interventional studies.

Significant experience in clinical science, clinical development, study implementation, epidemiology, real-world evidence, or related biopharmaceutical functions.

Strong experience authoring, reviewing, and approving clinical trial protocols and related study documentation.

Experience leading global or multi-country clinical studies through implementation and publication.

Extensive knowledge of interventional and non-interventional study designs, good clinical practice, applicable regulations, ethics, quality standards, and standard operating procedure-driven practices.

Demonstrated ability to interpret complex clinical and safety data and communicate findings effectively to diverse audiences.

Strong program leadership, stakeholder management, vendor oversight, decision-making, and team leadership skills, including experience using digital and artificial intelligence-enabled tools in a regulated environment.

Locations: Zurich, Switzerland

Base Salary Range: CHF177,400.00 - CHF243,980.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.

Worker Type: Employee. Worker Sub-Type: Regular Time. Type: Full time.

Takeda is an industry-leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda-ism - Integrity, Fairness, Honesty, and Perseverance - and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people's lives - including your own. Takeda is an equal opportunity employer.