Associate in Analytical Research and Development for Oligonucleotidesonucleotides

Roche; Basel; Vor Ort; CHF 30’000 - 80’000; Vollzeit

Zusammenfassung

A major pharmaceutical company in Basel is seeking an analytical development professional to enhance methods for quality assessments. This role involves developing and validating analytical techniques like HPLC and mass spectrometry, ensuring compliance with GxP guidelines, and collaborating with cross-functional teams. Ideal candidates will have significant experience in analytical instrumentation, strong writing skills, and a meticulous quality mindset. Proficiency in English is crucial, knowledge of German is a plus.

Qualifikationen

• Experience with techniques like chromatography and mass spectrometry.
• Interest in analytical development for oligonucleotides.
• Good documentation practices for regulatory filings.

Aufgaben

• Develop, improve, and validate analytical methods.
• Plan, execute, and document experiments collaboratively.
• Coordinate analytical activities for synthetic product development.

Kenntnisse

Hands-on experience with analytical instrumentation

Strong knowledge of LC-MS applications

Experience with large molecules/biologics analytics

Excellent scientific writing skills

Excellent digital skills

Proficient in English, German beneficial

Tools

HPLC

Mass Spectrometry (MS)

Jobbeschreibung

The Position

Behind every Roche product, whether in clinical trials or on the market, stands Pharma Global Technical Operations, a global organization with over 10,000 employees committed to delivering safe and high-quality medicines. “Pharma Technical Development,” a key part of this effort, is dedicated to developing innovative solutions for new therapies to meet patient needs. Within Pharma Technical Development, “Synthetic Molecules Technical Development” (PTDC) focuses on the technical development of our synthetic molecule pipeline and ensures the manufacture of clinical supplies for clinical studies.

This role resides in Analytical Research and Development for synthetic molecules, specializing in the creation of resource-efficient, cutting‑edge analytical methods using modern techniques like chromatography and mass spectrometry. The ultimate aim is to develop a robust quality control strategy to support product release for clinical trials and commercial supply, driving innovation and ensuring excellence every step of the way.

The opportunity

• Developing, improving, and validating analytical methods for quality assessment of materials, intermediates, active substances, and galenical forms.

• Planning, executing, and documenting experiments collaboratively, ensuring compliance with GxP guidelines and relevant SOPs.

• Work on end-to-end processes with cross-functional teams to drive efficient analytics and continuous improvement.

• Coordinating analytical activities, including sample management, for synthetic product development.

• Evaluating new technologies/methods and contributing to innovation projects.

• Authoring analytical documents such as procedures, validation reports, SOPs, and regulatory submission materials as needed.

Who you are

• Hands‑on experience with analytical instrumentation and techniques (e.g., HPLC, MS).

• Strong knowledge of LC‑MS applications and instruments is a plus.

• Interest or background in analytical development for oligonucleotides.

• Experience with large molecules/biologics analytics is an advantage.

• Strong scientific writing skills and good documentation practices for regulatory filings.

• Excellent digital skills, innovation mindset, and adaptability to fast‑changing environments.

• Self‑motivated, proactive, open‑minded, goal‑oriented, and a strong team player.

• Stringent quality mindset, excellent attention to detail, and knowledge of GxP requirements across clinical phases.

• Excellent English skills; German proficiency is beneficial.

Application documents – a pragmatic approach:

We kindly ask you to provide a brief explanation of what interests you about this position, a current CV, and your official educational certificates/proof of qualifications. No additional documents are required at this stage. Please note that no further documents can be added after the application has been submitted.

Apply now – we look forward to hearing from you!

Who we are

A healthier future drives us to innovate. Together, more than 100,000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.