Research Technician II

Universityhealthnetwork; Toronto; On-site; CAD 62,000 - 77,000; Full time

Benefits offered by this job

HOOPP pension

Flexible work environment

Development opportunities

On‑site gym and discounts

Job summary

The Princess Margaret Genomics Centre at University Health Network (UHN) in Toronto is seeking a Permanent Full‑time Research Technician II for our bulk genomics services team. You will perform library preparation, QC, and data entry, and collaborate with clients to ensure timely delivery of sequencing projects.

Qualifications include a Bachelor’s degree in Genomics or related field, 3+ years hands‑on experience, and familiarity with molecular biology techniques and LIMS.

Qualifications

• Bachelor's degree in Genomics, Molecular biology or related discipline required.
• Minimum 3 years hands‑on related experience required.
• At least 1 year in standard molecular biology techniques (PCR/qPCR, quantification, library prep) preferred.
• Experience with LIMS is an asset.
• Experience with Illumina DNA sequencing library construction is an asset.
• Willingness to learn new techniques and technologies.
• Excellent organizational and time management skills; able to work under deadlines.
• Strong interpersonal and team communication skills.

Responsibilities

• Perform genomics library preparation (RNA, whole genome, exome) with QC of input material and final products.
• Onboard samples from clients and communicate with them regarding progress.
• Construct DNA epigenetic profiling libraries (methylation).
• QC inputs by BioAnalyzer, Nanodrop, and fluorimetry; final QC of libraries.
• Enter sample and library data into LIMS and manage records.
• Operate Illumina NovaSeq X Plus sequencing platform and related workflows.

Skills

Molecular biology techniques

DNA/RNA QC

Time management

Team communication

Independence

Education

Bachelor's degree in Genomics or related discipline

Tools

LIMS

Illumina sequencing

Job description

Union: Non-Union

Number of Vacancies: 1

New or Replacement Position: Replacement

Site: Princess Margaret Cancer Centre

Department: Princess Margaret Genomics Centre

Reports to: Principal Investigator

Salary Range: $61,854 - $77,318 per annum

Hours: 37.5 hours per week

Shifts: Monday - Friday

Status: Permanent Full-time

Closing Date: November 13, 2026

Position Summary

The Princess Margaret Genomics Centre is seeking a Permanent Full-time Research Technician II, with potential for advancement within the PMGC team. As an integral member at the Genomics Centre, a core facility, the research technician must be dedicated and result-driven and will be involved in all aspects of service projects, following SOPs and meeting target deadlines. This role resides in our bulk genomics services team.

Duties

• Perform genomics library preparation (RNA, whole genome, exome). This includes QC of input material (RNA and DNA), following SOPs for construction, and QC of final products for internally constructed and externally submitted sequencing‑ready libraries.
• Onboarding of samples from and communication with clients.
• DNA epigenetic profiling (methylation) library construction.
• Input sample QC by BioAnalyzer, Nanodrop, and fluorimetry.
• Final library QC by BioAnalyzer.
• Entry of sample and library information into LIMS.
• Illumina NovaSeq X Plus loading and operation.

Minimum Requirements

• At minimum, Bachelor' degree in Genomics, Molecular biology or related discipline is required.
• At least three (3) years of hands‑on related experience required.
• At least one (1) year of experience with standard molecular biology laboratory techniques, such as PCR reaction set up and purification, qPCR reaction assembly and data interpretation, nucleic acid quantification by spectrophotometry and fluorimetry, sequencing library construction, an asset.
• Experience with using LIMS (Laboratory Information Management System) is an asset.
• Experience with Illumina DNA sequencing library construction workflows and instrument operation is an asset.
• A willingness to learn new techniques and technologies is required.
• Excellent organizational and time management skills is required.
• Ability to work independently and accurately under deadlines is required.
• Excellent interpersonal and communication skills in a team environment is required.

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages.
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/ ).
• Close access to Transit and UHN shuttle service.
• A flexible work environment.
• Opportunities for development and promotions within a large organization.
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on‑site gyms, etc.).

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

UHN uses email to communicate with selected candidates.

At University Health Network (UHN), artificial intelligence technologies may be used to assist in the screening, assessment, and selection of candidates for this position.

Please be advised that a Criminal Record Check may be required of the successful candidate.

Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.