Principal Statistical Programmer

IQVIA; Mississauga; On-site; CAD 164,000 - 233,000; Full time

Job summary

IQVIA in Mississauga is seeking a Principal Statistical Programmer to provide full end-to-end statistical programming support across clinical development programs. The role requires deep technical expertise and leadership, covering SDTM, ADaM, TLF development, and regulatory submission support.

You will ensure high-quality deliverables, help maintain programming standards, and guide other programmers, with collaboration across Biostatistics, Data Management, Clinical Operations, and Regulatory

Qualifications

• Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field.
• Extensive experience as a statistical programmer with Principal-level responsibilities.
• Strong hands-on experience with base SAS and Advanced SAS with SAS Macros.

Responsibilities

• Provide end-to-end statistical programming support for clinical studies from study setup through submission.
• Lead and perform development and validation of programming deliverables.
• Ensure all deliverables are compliant with CDISC standards and regulatory requirements.
• Support regulatory submissions (FDA, EMA), including define.xml and submission-ready datasets.
• Serve as a Principal-level programmer, providing technical leadership and guidance to other programmers.
• Contribute to and help maintain programming standards, macros, and validation processes.
• Review and approve programming deliverables to ensure accuracy and quality.
• Collaborate with Biostatistics, Data Management, Clinical Operations, and Regulatory teams.
• Proactively identify risks and propose compliant solutions within timelines.

Skills

Statistical programmer

Principal-level responsibilities

Base SAS

Advanced SAS

SAS Macros

CDISC standards

Education

Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field

Job description

Position Summary

We are seeking a Principal Statistical Programmer to provide full end‑to‑end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands‑on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support. The Principal Statistical Programmer will serve as a subject matter expert, ensure high‑quality deliverables, and contribute to programming standards and best practices.

Key Responsibilities

• Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
• Lead and perform development and validation of:
• Ensure all deliverables are compliant with CDISC standards and regulatory requirements
• Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
• Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
• Contribute to and help maintain programming standards, macros, and validation processes
• Review and approve programming deliverables to ensure accuracy, consistency, and quality
• Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
• Proactively identify risks and propose efficient, compliant solutions within timelines

Required Qualifications

• Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
• Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
• Strong hands‑on experience with:
• Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
• In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
• Proven ability to manage complex studies independently from start to finish

IQVIA est un fournisseur mondial de premier plan de services de recherche clinique, d’informations commerciales et de renseignements sur les soins de santé pour les secteurs des sciences de la vie et de la santé. IQVIA se consacre à accélérer le développement et la commercialisation de traitements médicaux innovants pour aider à améliorer les résultats des patients et la santé de la population dans le monde entier. Pour en savoir plus, visitez https://jobs.iqvia.com

IQVIA est fière d’être un employeur souscrivant au principe de l’égalité d’accès à l’emploi.

Tous les candidats qualifiés seront pris en considération pour un emploi sans égard à la race, la couleur, la religion, le sexe, l’orientation sexuelle, l’identité de genre, l’origine nationale, le handicap, l’âge, l’état matrimonial ou tout autre statut protégé par la loi applicable.

Des mesures d’adaptation pour les candidats handicapés sont disponibles sur demande dans tous les aspects du processus de recrutement.

IQVIA is proud to be an equal opportunity employer.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, marital status, or any other status protected by applicable law.

Accommodations for applicants with disabilities are available in all aspects of the recruitment process upon request.

If you have a disability that requires an accommodation, we encourage you to contact our Talent Acquisition Team at: [e-mail], so that IQVIA can support your participation in the recruitment process.

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud.

All information and credentials submitted in your application must be truthful and complete.

Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law.

We appreciate your honesty and professionalism.

Please note that we may use artificial intelligence (AI) in the processing of your application.

However, we only use AI to assist our recruitment team with the screening or assessment of candidacies, and not as a substitute for human decision-making.

Veuillez noter qu’il est possible que nous utilisions l’intelligence artificielle (IA) dans le traitement de votre candidature. Cependant, nous utilisons l’IA uniquement pour aider notre équipe de recrutement à sélectionner ou à évaluer les candidatures, et non pas pour remplacer la prise des décisions par les membres de notre équipe.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

The potential base pay range for this role, when annualized, is $118,300.00 - $168,300.00.

The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time).

Benefits

• Selon le poste offert, des régimes d’incitation, des primes et/ou d’autres formes de rémunération peuvent être proposés, en plus d’une gamme d’avantages sociaux liés à la santé, au bien‑être et/ou d’autres bénéfices.
• Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and wellness and/or other benefits.

La fourchette salariale de base potentielle pour ce poste, annualisée, est de $118,300.00 - $168,300.00.

Le salaire de base réel offert peut varier selon plusieurs facteurs, notamment les qualifications liées à l’emploi telles que les connaissances, les compétences, la formation et l’expérience; l’emplacement; et/ou l’horaire (temps plein ou temps partiel).