Chemist, Physical Properties RD7

Apotex Inc.; Toronto; On-site; CAD 63,000 - 106,000; Full time

Job summary

Apotex Inc. in Toronto is seeking a senior analytical chemist to perform R&D and commercial release tests in a GMP-compliant environment with strong data integrity. You will develop and validate methods for analyzing active and inactive ingredients, interpret complex data, and generate scientific reports.

The role involves various instrumental techniques and collaboration with the labs team. The position requires advanced analytical chemistry expertise, excellent communication skills, and a

Qualifications

• Post-secondary education in analytical or pharmaceutical sciences.
• Experience in a pharmaceutical R&D lab with physical property testing.
• Knowledge of peptides preferred.
• Strong analytical, technical, teamwork and communication skills.

Responsibilities

• Develop, validate and transfer testing methods for R&D and commercial release. Issue method development summaries, validation and transfer reports.
• Establish and develop testing strategy using state-of-the-art Physical Properties laboratory instruments.
• Evaluate drug substances, products and excipients and advise on polymorphic forms, particle size and other physical properties.
• Develops and implements crystalline form preparation and characterization using PXRD, TGA/DSC, microscopy, particle size analysis, and related techniques.
• Maintain strong relationships with external providers/vendors and customers.
• Identify root causes of challenges and propose new problem-solving approaches.
• Establish performance criteria for analytical instrumentation/systems.
• Keep updated with new analytical techniques through literature and training.
• Demonstrate corporate values in performance and interactions.
• Performs additional duties as assigned and trains new chemists on lab equipment.

Skills

Analytical chemistry

Physical chemistry

Materials chemistry

Pharmaceutical sciences

Education

Bachelor's degree in Analytical/Chemistry

Master's degree in Chemistry

PhD in Pharmaceutical Sciences

Tools

ICP-OES

ICP-MS

XRD

DSC

FT-IR

NIR

BET

DLS

Job description

About Apotex Inc.

Apotex is a Canadian-based global health company. We improve everyday access to affordable, innovative medicines and health products for millions of people worldwide, with a broad portfolio of generic, biosimilar, innovative branded pharmaceuticals and consumer health products. Headquartered in Toronto, with regional offices globally, including in the United States, Mexico and India, we are the largest Canadian-based pharmaceutical company and a health partner of choice for the Americas for pharmaceutical licensing and product acquisitions.

About Apotex Inc.

Apotex is a Canadian-based global health company. We improve everyday access to affordable, innovative medicines and health products for millions of people worldwide, with a broad portfolio of generic, biosimilar, innovative branded pharmaceuticals and consumer health products. Headquartered in Toronto, with regional offices globally, including in the United States, Mexico and India, we are the largest Canadian-based pharmaceutical company and a health partner of choice for the Americas for pharmaceutical licensing and product acquisitions.

For more information visit: www.apotex.com .

Job Summary

Perform R&D and Commercial release tests in compliance with GMP and data integrity requirements. Responsible for developing and validate methods for analyzing pharmaceutical active and inactive ingredients using a wide variety of instruments. Interprets analytical data and generates complex scientific reports. Performs unknown particles identification and specialized type of investigations on physical properties.

Job Responsibilities

• Develop, validate and technology transfer testing methods for R&D and commercial release. Issue method development summary, validation and technology transfer protocols and method validation and technology transfer reports.
• Establish and develop testing strategy by using state-of-the-art Physical Properties laboratory instruments for pharmaceutical drug substances and products. Develop and support other Apotex labs special investigation requests with various analytical techniques as required.
• Evaluate pharmaceutical drug substance, drug products and excipients and provide expert advice on the decision making of polymorphic forms, material particle size, and other physical properties information to management in the new product development, submission, Product Life Cycle Management (PLCM) and patent related issues.
• Develops and implements strategies and work plans in the crystalline form preparation, identification and characterization by various techniques including Powder x-ray diffraction, Thermal analysis (TGA/DSC), Microscope, Particle size analysis, laser particle size and DLS, FT-IR, Microscope FT-IR, FT-IR/NIR image system, ATR, Surface/material characterization (Nitrogen BET surface area and dynamic vapor adsorption), Inductively Coupled Plasma (ICP) – ICP-OES and ICP-MS and the use of general analytical instruments.
• Maintain strong relationships with external providers/vendors and customers.
• Identifies root causes of challenge projects. Investigates and recommends the usage of new or unconventional problem solving techniques to the next level.
• Establishes performance criteria for new and existing analytical instrumentation/systems.
• Keeps updated with new analytical techniques through literature, seminars, workshops etc.
• Demonstrates corporate values in the performance of the work and interactions with others.
• Performs additional related duties, as assigned, in accordance with job responsibilities and necessary departmental objectives.
• Training new chemist on various lab equipments.

Job Requirements

• Recognized post secondary education in analytical chemistry, material chemistry, material engineering, organic chemistry, pharmaceutical sciences, or related field.
• BSc with 5 years or MSc with 3 years or PhD with minimum 1 year experience in a pharmaceutical lab in an R&D environment with focus on physical property testing.
• Preferred to have knowledge in peptides.
• Advanced knowledge of analytical and physical chemistry, pharmaceutical solid dosage forms.
• Demonstrated technical proficiency, scientific creativity, teamwork, and independent thought.
• Excellent written and verbal communication skills.

At Apotex, we are committed to fostering a welcoming andaccessible work environment, where all everyone feels valued, respected, and supported to succeed.

We offer accommodation for applicants with disabilities as part of its recruitment process. If you are contacted to arrange for an interview or testing, please advise us if you require an accommodation.

The hiring range for this position is $63,482 - $105,804 CAD per year. The final agreed-upon salary may vary based on factors such as job-related knowledge, skills and experience.

We are looking for top talent. If your qualifications differ from those listed above, the scope of work and final agreed-upon salary may be adjusted to reflect your individual qualifications.

The Apotex Total Rewards package goes beyond base salary. Apotex offers bonus programs based on your position in the organization, you can excel based on our pay-for-performance philosophy. With comprehensive benefits, a pension plan to help you save for retirement and learning and development opportunities, we provide a comprehensive package for your personal and professional development.

Apotex will use artificial intelligence to screen, select and/or assess your application for this job.

This job posting is for a role that is currently available and vacant at Apotex.