Lead Analytical Scientist, RNA & LNP Platforms

Aurora Biosynthetics; Sydney; On-site; AUD 125,000 - 150,000; Full time

Benefits offered by this job

Biotech program

Collaborative environment

National and international impact

Job summary

Aurora Biosynthetics is hiring a Principal Scientist, Analytical Development to lead assay development and analytical testing for pDNA, mRNA, and targeted LNP platforms at our Sydney facility. The role will drive development, optimization, and transfer of analytical methods into GMP QC labs, collaborating across Process Development, Manufacturing, QC/QA, and external partners.

The ideal candidate has 3+ years in industry lab setting, expertise in mRNA-LNP analytics, and strong data

Qualifications

• Bachelor's or Master’s degree in biochemistry, molecular biology, or related field.
• 3+ years lab research experience in industry.
• Hands-on experience with mRNA-LNP analytics: flow cytometry, PCR, ELISA, NanoOrange, Ribogreen, DLS.

Responsibilities

• Develop, optimize, and execute analytical assays for mRNA and LNP/tLNP characterization.
• Perform analytical testing at multiple stages to monitor quality attributes (size, PDI, encapsulation).
• Develop cell-based potency assays for CAR expression and function.
• Analyze data with statistical tools, ensuring traceability and documentation for tech transfer and regulatory submissions.
• Execute SOPs and assay protocols to ensure robust results.
• Maintain lab readiness; manage inventory and materials for analytical studies.
• Collaborate cross-functionally to integrate assay data into development decisions.

Skills

Flow cytometry

PCR

ELISA

NanoOrange

RiboGreen

DLS

Cell-based potency assays

CAR functional assays

Education

BS/MS in Biochemistry, Molecular Biology, or related

Job description

Aurora Biosynthetics is hiring a Principal Scientist, Analytical Development to lead assay development and analytical testing for pDNA, mRNA, and targeted LNP platforms at our Sydney facility. The role will drive development, optimization, and transfer of analytical methods into GMP QC labs, collaborating across Process Development, Manufacturing, QC/QA, and external partners.

The ideal candidate has 3+ years in industry lab setting, expertise in mRNA-LNP analytics, and strong data